Results 131 to 140 of about 2,458,887 (300)
The Downside of Standardized Testing [PDF]
, 2013 Children in the United States are tested “to an extent that is unprecedented in our history and unparalleled anywhere else in the world.” The federal No Child Left behind Act has triggered a standardized testing “explosion,” the repercussions of which ...
Intschert, Nicole
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
, 2018 Across the empirical sciences, few statistical procedures rival the popularity of the frequentist t-test. In contrast, the Bayesian versions of the t-test have languished in obscurity. In recent years, however, the theoretical and practical advantages of
Gronau, Quentin F. +2 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Information System Construction and Application of the Standardized Test Center Based on Internet
Dianxin kexue, 2015 Based on the construction of internet information system，the basic specification of the standardized test center was studied and a set of comprehensive business requirements including monitoring，communication，audio，video and education examination ...
Lu Zhang +3 more
doaj +2 more sources
Making a Connection between Student Achievement, Teacher Accountability, and Quality Classroom Instruction [PDF]
, 2008 The importance of standardized test results is becoming more prevalent in the structure of classroom instruction and the operation of schools throughout the nation due to pressure on educators and students from various levels of authority.
Ballard, Kelli, Bates, Alan
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Characteristics of 30-centimeter mercury ion thrusters [PDF]
The technology development of the 30 centimeter J series mercury ion thruster for prime propulsion application in solar electric propulsion systems is described. Thruster design is reviewed.
Dugeroff, C. R. +2 more
core +1 more source