Results 141 to 150 of about 2,458,887 (300)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Asymptotic behaviour of the CUSUM of squares test under stochastic and deterministic time trends [PDF]
We undertake a generalization of the cumulative sum of squares (CUSQ) test to the case of non-stationary autoregressive distributed lag models with quite general deterministic time trends.
B. Nielsen, Jouni Sohkanen
core
Milwaukee Longitudinal School Choice Evaluation: Annual School Testing Summary Report 2010-11 [PDF]
, 2012 Effective at the start of the 2010-11 school year, 2009 Wisconsin Act 28 requires private schools participating in the Milwaukee Parental Choice Program (MPCP) to administer the state test, the Wisconsin Knowledge and Concepts Examinations (WKCE) in ...
Jacob, Anna M., Wolf, Patrick J.
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Equivalence Test and Sample Size Procedures for Standardized Mean Differences in ANCOVA Studies
Journal of Probability and StatisticsThis article presents exact equivalence tests of standardized mean differences in ANCOVA studies. As an alternative to the traditional hypothesis testing for confirming the existence of substantial differences, the proposed equivalence procedure helps ...
Gwowen Shieh
doaj +1 more source
What test scores can and cannot tell us about the quality of our schools. [PDF]
"What Test Scores Can and Cannot Tell Us about the Quality of Our Schools," by Ted Crone, recognizes that how to best judge the quality of our schools is a thorny issue.
Theodore M. Crone
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
An Online Recruitment System for Economic Experiments [PDF]
In this paper we introduce the Online Recruitment System for Economic Experiments (ORSEE). With this software experimenters have a free, convenient and very powerful tool to organize their experiments and sessions in a standardized way.
Greiner, Ben
core +1 more source