Results 221 to 230 of about 1,661,930 (349)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Standardization of radon measurements: II. Accuracy and proficiency testing

, 1990
J.M. Matuszek
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Evaluation of the cardiorespiratory fitness in Fontan patients by a standardized stair climbing test in comparison to the six minute walking test and cardiopulmonary exercise testing (CPET)

Anne Lentz, Maurice Pablo Mall, Johanna Wander, Felix Sebastian Oberhoffer, Guido Mandilaras, André Jakob, Nikolaus Haas, Simone Katrin Manai   +7 more
openalex   +1 more source

Standardization of a latex agglutination test for coproantigen detection of Fasciola sp. in bovine cattle stool

, 2017
Lina Paola Orejarena Ávila, Erika Marcela Inguilan Benavides, Leonardo Padilla Sanabria, Delia Piedad Recalde-Reyes, Carlos Andrés Rodríguez-Salazar, Jhon Carlos Castaño Osório   +5 more
openalex   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Relationship Between Humor and Subjective Well-Being: The Mechanism of the Connotation of Humor. [PDF]

Behav Sci (Basel)
Cai Y, Zhang J, Leng M, Guan Q, Zhou X, Zhou S, Zhou W.   +6 more
europepmc   +1 more source

Objectively Assessed Factors Affecting Gender Differences in Olfactory Function including hormonal differences: A Cross-Sectional Study Using a Standardized Testing Protocol

Riad, Hany Amin
openalex   +1 more source