Results 111 to 120 of about 6,899,160 (286)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Hybrid System for Driver Assistance Using Computer Vision Methods

open access: yesStandards
Driver fatigue and drowsiness are the causes of many road accidents. In this work, a low-cost hybrid system is proposed for determining driver fatigue level based on four metrics: last sleep quality, blinking rate, heart rate variation, and yawning.
Liviu Octavian Mafteiu-Scai   +1 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Leadership Discourse and Sustainability Reporting in Fast Fashion: A Longitudinal Topic Modelling and KPI Analysis

open access: yesStandards
Corporate sustainability reporting is increasingly scrutinised as stakeholders’ demand credible commitments to environmental and social performance, especially in sectors where unsustainable practices are pervasive. The aim of this research is to examine—
Julia Marques de Medeiros   +4 more
doaj   +1 more source

High precision cryogenic thermal conductivity standards [PDF]

open access: yes, 1970
New apparatus allows accurate simultaneous measurement of thermal conductivity, electrical resistivity, and thermopower for technically important materials, such as new or uncommon alloys. A list of materials investigated is presented.
Hust, J. G.   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Optimizing FNP Clinical Education: A Path Toward Standardized Training and Sustainable Workforce Development

open access: yesStandards
The demand for family nurse practitioners (FNPs) continues to rise, yet inconsistencies in clinical education have led to significant variability in graduate preparedness.
Jessica Nishikawa, Tandrea Jackson
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Workmanship standards for fusion welding [PDF]

open access: yes, 1967
Workmanship standards manual defines practices, that adhere to rigid codes and specifications, for fusion welding of component piping, assemblies, and systems.
Phillips, M. D.
core   +1 more source

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