Results 141 to 150 of about 7,366,072 (339)

A Risk Analysis Model for Biosecurity in Brazil Using the Analytical Hierarchy Process (AHP)

open access: yesStandards
This study proposes a risk analysis model based on the principles of ISO 31000 and decision theory for biological agents with potential for offensive use in Brazil. Bibliographic research was conducted on the main models already published on the subject.
Fillipe Augusto da Silva   +5 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Smart Education for Corporate Sustainability Reporting

open access: yesStandards
The European Union’s Corporate Sustainability Reporting Directive expanded its Non-Financial Reporting Directive requirements to companies with over 250 employees, mandating their sustainability reporting from 2025.
Peter Glavič   +7 more
doaj   +1 more source

Standards for Reporting Qualitative Research: A Synthesis of Recommendations

open access: yesAcademic medicine : journal of the Association of American Medical Colleges, 2014
Bridget C. O’Brien   +4 more
semanticscholar   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Asymmetric Effect of Natural Resource Exploitation on Climate Change in Resource-Rich African Countries

open access: yesStandards
This study investigated the asymmetric impact of natural resource exploitation on climate change in resource-rich African countries, based on panel data from 1980 to 2022.
Adewale Samuel Hassan
doaj   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

EU Environmental Protection in Regard to Sustainable Development: Myth or Reality?

open access: yesStandards
According to conclusions agreed to in the 1995 Report of the World Summit for Social Development and the 2015 Sustainable Development Summit, seventeen sustainable development goals (SDGs) have been ratified and published as the 2030 Agenda for ...
Ivana Špelić, Alka Mihelić-Bogdanić
doaj   +1 more source

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