Results 61 to 70 of about 2,050,460 (296)

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Assessing the Environmental Sustainability Corridor: Carbon Emissions in Relation to Gold Price, Economic Growth, Foreign Direct Investment, and Renewable Energy Consumption

Standards
The growing concerns about global warming and its perceived influence on economic sustainability require a reassessment of the environmental consequences of gold mining, with a special focus on BRICS countries: Brazil, Russia, India, China, and South ...
Mehdi Seraj, Ayantayo Rukayat Olaide
doaj   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Structured Representation of Pre-Defined Information Backflow in Standards and Directives

Standards
This publication examines the representation of information within test specifications and formulas defined in standards and directives. This information often pre-defines not only the tests and requirements to be conducted but also the information ...
Max Layer, Janosch Luttmer, Arun Nagarajah, Ralph Stelzer   +3 more
doaj   +1 more source

Femtosecond time synchronization of optical clocks off of a flying quadcopter

Nature Communications, 2019
Optical clock networks have many applications from precision time keeping, sensing to fundamental physics. Here the authors demonstrate robust and free-space femtosecond time synchronization of optical clocks via a moving quadcopter.
Hugo Bergeron, Laura C. Sinclair, William C. Swann, Isaac Khader, Kevin C. Cossel, Michael Cermak, Jean-Daniel Deschênes, Nathan R. Newbury   +7 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Adopting Sustainability Competencies in Management Education—A Scoping Review of Progress

Standards
There is growing urgency to address society’s complex issues, many of which are incorporated within the Sustainable Development Goals (SDGs). Higher education has a special role and a responsibility to support and promote these goals and to prepare ...
Patricia MacNeil, Anshuman Khare
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

The Impact of ESG Certifications on Class A Office Buildings in Madrid: A Multi-Criteria Decision Analysis

Standards
This study investigates the impact of Environmental, Social, and Governance (ESG) certifications on the performance of Class A office buildings within Madrid’s Central Business District (CBD). Employing a Multi-Criteria Decision Making (MCDM) methodology,
Alfonso Valero
doaj   +1 more source

Standards

ALT-J, 1993
One of the aims of ALT is to promote good practice in the use of learning technology within higher education. Few would not subscribe to this aim, but proclaiming it without a full awareness of the problems it entails is of the same order as proclaiming one's commitment to Peace without further comment.
openaire   +4 more sources