Results 81 to 90 of about 2,050,460 (296)

Optimizing FNP Clinical Education: A Path Toward Standardized Training and Sustainable Workforce Development

open access: yesStandards
The demand for family nurse practitioners (FNPs) continues to rise, yet inconsistencies in clinical education have led to significant variability in graduate preparedness.
Jessica Nishikawa, Tandrea Jackson
doaj   +1 more source

PKI standards

open access: yesInformation Security Technical Report, 2000
This paper provides a review of the current state of the art in standards for Public Key Infrastructures. The main focus of the paper is the recent work by the Internet Engineering Task Force, ITU-T, and ISO/IEC.
openaire   +6 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Beyond Compliance: A Deep Dive into Improving Sustainability Reporting Quality with LCSA Indicators

open access: yesStandards
This study addresses the critical need for improved sustainability reporting in the construction sector, focusing on the integration of Life Cycle Sustainability Assessment (LCSA) indicators to enhance reporting quality and promote standardization.
Suzana Ostojic   +3 more
doaj   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Are Stakeholders’ Opinions Redundant?

open access: yesStandards
Decision-making, bringing in the opinions of several stakeholders, may be a rather time- and resource-demanding process. Partial order-based methods like generalized linear aggregation (GLA) and average ranking appear as advantageous tools for ...
Lars Carlsen
doaj   +1 more source

Standard Methods for the Examination of Dairy Products [PDF]

open access: bronze, 1949
A. H. Robertson   +5 more
openalex   +1 more source

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