Results 81 to 90 of about 2,050,460 (296)
The demand for family nurse practitioners (FNPs) continues to rise, yet inconsistencies in clinical education have led to significant variability in graduate preparedness.
Jessica Nishikawa, Tandrea Jackson
doaj +1 more source
An Investigation of the League of Nations Standard Requirements for Schick Toxin [PDF]
E. M. Taylor, P. J. Moloney
openalex +1 more source
This paper provides a review of the current state of the art in standards for Public Key Infrastructures. The main focus of the paper is the recent work by the Internet Engineering Task Force, ITU-T, and ISO/IEC.
openaire +6 more sources
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Beyond Compliance: A Deep Dive into Improving Sustainability Reporting Quality with LCSA Indicators
This study addresses the critical need for improved sustainability reporting in the construction sector, focusing on the integration of Life Cycle Sustainability Assessment (LCSA) indicators to enhance reporting quality and promote standardization.
Suzana Ostojic+3 more
doaj +1 more source
Standard Methods of The Division of Laboratories And Research of The New York State Department of Health [PDF]
openalex +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
Are Stakeholders’ Opinions Redundant?
Decision-making, bringing in the opinions of several stakeholders, may be a rather time- and resource-demanding process. Partial order-based methods like generalized linear aggregation (GLA) and average ranking appear as advantageous tools for ...
Lars Carlsen
doaj +1 more source
Standard Methods for the Examination of Dairy Products [PDF]
A. H. Robertson+5 more
openalex +1 more source