Results 51 to 60 of about 2,450,081 (301)

Methodological purpose to incorporate the knowledge creation into management systems in Government institutions

Signos, 2015
Colombian Government established the quality management and internal control as mandatory tools of management, according to Quality Technical Standards NTCGP:1000 and the Standard Model of Internal Control, incorporated by government in decrees 4485 of ...
Carolina Orjuela Russi, Rosario del Pilar Ramos Díaz, Gloria Matilde Torres Cruz   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Legal conditions of the principles of management control in the public finance sector and the rules of coordination of control

Journal of Modern Science
The principles of management control and coordination of management control are described in Section I, Chapter 6 - Articles 68 - 71 of the Act of August 27, 2009 on Public Finance.
Łukasz Wojciechowski, Piotr Waszak, Angelika Koman-Bednarczyk, Wińczysław Jastrzębski, Tomasz Wołowiec   +4 more
doaj   +1 more source

Method of implementation of independent risk evaluation and internal control [PDF]

E3S Web of Conferences, 2019
Internal control in accordance with international and federal standards is a process that is organized and implemented by the management of an enterprise, its employees and representatives of the owner. Model of development of the internal control system.
Musaeva R. A., Tikhonova R. U., Yevstigneeva L. M., Nigmatzyanova L. R., Derbeneva A. A.   +4 more
doaj   +1 more source

Reducing violence in severe mental illness: randomised controlled trial of intensive case management compared with standard care [PDF]

BMJ, 2001
To establish whether intensive case management reduces violence in patients with psychosis in comparison with standard case management.Randomised controlled trial with two year follow up.Four inner city community mental health services.708 patients with established psychotic illness allocated at random to intervention (353) or control (355) group ...
Walsh, E, Gilvarry, C, Samele, C, Harvey, K, Manley, C, Tyrer, P, Creed, F, Murray, R, Fahy, T   +8 more
openaire   +4 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

FEATURES OF INTERNAL/MANAGERIAL CONTROL IN PUBLIC ORGANIZATIONS [PDF]

Journal of Defense Resources Management, 2014
Control aims at the protection of patrimony, the quality of information, and the increase of performance and application of guidelines coming from the management of the public organization.
Gheorghe MINCULETE, Maria-Ana CHISEGA-NEGRILA   +1 more
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Control of Sale in Function of Improving Business in Company

Acta Economica, 2007
Control as a phase of process of managing has for a goal continually measuring success of planned decisions, with relation to business vision, mission, plans and programs, and also efficiency of doing measures of corrections when that is necessary.
Анита Шимунџа
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