Results 51 to 60 of about 1,012,999 (323)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Quaestio FactiThe work comments on Della Torre’s essay about the evolution of the reasonable doubt criminal standard of proof. By going through the main claims of the essay, which is both historical and theoretical, the work contends that the essay clarifies (and ...
Giovanni Tuzet
doaj +1 more source
Gong-kuang zidonghua, 2018 Status of microcomputer protection device for mine-used high-voltage explosion-proof switch was introduced from aspects of hardware structure and basic functions.
LU Donggui, RONG Xiang, ZENG Ke
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Plausibility and Probability in Juridical Proof [PDF]
, 2019 This note discusses three issues that Allen and Pardo believe to be especially problematic for a probabilistic interpretation of standards of proof: (1) the subjectivity of probability assignments; (2) the conjunction paradox; and (3) the non-comparative
Di Bello, Marcello
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
, 2011 Optimization of energy consumption in future intelligent energy networks (or Smart Grids) will be based on grid-integrated near-real-time communications between various grid elements in generation, transmission, distribution and loads.
Chin, Woon Hau +8 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
THE STANDARDS OF PROOF AND THE SEARCH FOR MORE OBJECTIVITY IN THE DECISION ABOUT THE FACTS
Revista Eletrônica de Direito Processual, 2021 The article aims to untangle the concept of standard of proof, properly inserting it in the context of decision-making, presenting its main functions and identifying its ability to make the decision on the facts in the decision process more objective.
Ravi Peixoto
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Правовое государство: теория и практикаIn order to effectively fulfil state tasks in the field of activities of criminal justice authorities, a legislative definition of a reasonable correlation between public and private principles is required both in criminal procedure legislation and in ...
AZAROV Vladimir Alexandrovich
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