Results 151 to 160 of about 1,361,200 (287)

Reduced total arterial compliance in frail older adults is associated with orthostatic blood pressure variability but not baroreflex sensitivity. [PDF]

J Frailty Aging
de Matos DG, Aidar FJ, Nunes-Silva A, Peringod G, Giambusso V, Romero-Ortuno R, Duhamel TA, Villar R.   +7 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Standing Bear

[was 1397-7] Standing Bear, wife & child ...

core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Predictability of Postural and Standing Balance from a Clinical Impairment Battery in Children with Cerebral Palsy: A Cross-Validated Regression and Hurdle Model Analysis. [PDF]

Bioengineering (Basel)
Salman AF, Al-Nabulsi JI, Olamat A, Abdelaziem FH, El-Talawy HAEA, Fayed AE.   +5 more
europepmc   +1 more source

Stand and deliver [PDF]

Nature, 2010
openaire   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

37 Exploring freedom and human rights of children and young persons with albinism in Malawi

BMJ Paediatrics Open
Paul Lynch, Christopher Hand, Bonface Massah, Tuntufye Juma, Jenipher Mbukwa-Ngwira, Owen Mchekeni, Lexxa Zachariah   +6 more
doaj   +1 more source

Passive ankle exoskeleton assistance selectively modulates triceps surae neural control during balance. [PDF]

J R Soc Interface
Hamard R, Hug F, Dick TJM.
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source