Results 171 to 180 of about 1,075,706 (313)

Standing Out and Standing Up

open access: yes
Adolescence is a period of substantial physical, emotional, and social development. Under the influence of puberty, adolescents’ bodies change, and so does the developing brain. Hormonal changes increase sensitivity to rewards and social feedback, while cognitive control systems continue to mature well into adulthood.
openaire   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Committee on Academic Standing Minutes December 3, 1975

open access: yes, 1975
Minutes for the meeting of the Committee on Academic Standing on December 3 ...
Bronx Community College Committee on Academic Standing
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Committee on Academic Standing Minutes February 15, 1984

open access: yes, 1984
Minutes for the meeting of the Academic Standing on February 15 ...
Bronx Community College Committee on Academic Standing
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Committee on Academic Standing Minutes March 4, 2004

open access: yes, 2004
Minutes for the meeting of the Committee on Academic Standing on March 4 ...
Bronx Community College Committee on Academic Standing
core   +1 more source

A New Method for Measuring Structural Limb-Length Discrepancy: A Quasi-Experimental Study. [PDF]

open access: yesJ Clin Med
Atallah H   +7 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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