The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A Case Report on Balance Progress in a Patient with Body Lateropulsion: Focusing on Vestibulo-ocular Reflex and Subjective Visual Vertical. [PDF]
Saisu K, Igarashi T, Hayashi S, Kamo T.
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
KT-YOLO: A multi-convolution kernel collaboration model for dense Hu sheep behavior detection. [PDF]
Zhang S, Chang H, Wu Z, Wu G, Ji R.
europepmc +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Effect of a 2-h daily exit on milk quality, activities and outside behavior of lactating cows. [PDF]
Arango S +7 more
europepmc +1 more source
From routine full-spine radiographs to decision-oriented Risser stratification: an interpretable deep-learning approach. [PDF]
Wang Z +5 more
europepmc +1 more source
A supine exercise program linking trunk stability with lower extremity coordination is associated with improved body balance and agility: A study using randomized crossover and pre-post trial designs. [PDF]
Atomi A +7 more
europepmc +1 more source
Localized Infrared Hyperthermia as an Adjunctive Therapy for Long-Standing Hailey-Hailey Disease: A Case Report. [PDF]
Wu H +5 more
europepmc +1 more source

