Results 161 to 170 of about 126,096 (348)
Cold Plasma Activity Against Biofilm Formation of Prosthetic Joint Infection Pathogens
PathogensPeriprosthetic joint infections occur in 1–2% of all patients undergoing prosthetic joint surgeries. Although strong efforts have been made to reduce infection rates, conventional therapies like one- or two-stage revisions have failed to lower the ...
Christopher Spiegel +4 more
doaj +1 more source
STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis
Advanced Science, EarlyView.STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen +19 more
wiley +1 more source
MicroorganismsAs the mobile cassette carrier of the methicillin resistance gene mecA that is transported across staphylococci species, the evolution and origin of Staphylococcal Cassette Chromosome mec (SCCmec)—and in particular, the composition of mecA and SCCmec ...
Huawei Wang, Jinxing He
doaj +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Advanced Science, EarlyView.Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source
Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics
Advanced Science, EarlyView.Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan +5 more
wiley +1 more source
Антибиотики и Химиотерапия, 2020 The dynamics of isolation of staphylococci and enterococci from clinical material of patients and their antibiotic susceptibility within a 5-year period (2005-2009) was analysed.
N. S. Bogomolova +3 more
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Advanced Science, EarlyView.A self‐adaptive and biomimetic nanocomposite hydrogel is engineered to orchestrate dual‐targeting and on‐demand H2S gasotransmission for multifactorial diabetic wound therapy. By seamlessly integrating antibacterial, antioxidant, anti‐inflammatory, immunoregulatory, and pro‐angiogenic functions within a single platform, this hydrogel dynamically ...
Kefan Wu +8 more
wiley +1 more source
Антибиотики и Химиотерапия, 2020 Amidation of the end carboxyl group of eremomycin and vancomycin by pinacolinic 4- or 3-amino methyl phenyl boron acids esters in the presence of the condensing reagent PyBOP resulted in formation of novel carboxamides of the antibiotics (IIIa-VIa ...
E. N. Bychkova +4 more
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