Results 41 to 50 of about 81,209 (295)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Clinical and Bacteriological Analyses of Biofilm-Forming Staphylococci Isolated from Diabetic Foot Ulcers

, 2023
Hend Mamdoh,1 Khaled M Hassanein,2 Lobna Farag Eltoony,3 Walaa A Khalifa,3 Entsar Hamed,2 Taher Obaid Alshammari,4 Doaa M Abd El-Kareem,5 Mohamed A El-Mokhtar2 1Department of Microbiology and Immunology, Faculty of Pharmacy, Sphinx University, New Assiut,
Mamdoh H, Hassanein KM, Khalifa WA, Eltoony LF, El-Mokhtar MA, Hamed E, Alshammari TO, Abd El-Kareem DM   +7 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A look at staphylococci from the one health perspective

International Journal of Medical Microbiology
Staphylococcus aureus and other staphylococcal species are resident and transient multihost colonizers as well as conditional pathogens. Especially S. aureus represents an excellent model bacterium for the “One Health” concept because of its dynamics at ...
Christiane Cuny, Franziska Layer-Nicolaou, Guido Werner, Wolfgang Witte   +3 more
doaj   +1 more source

Antibacterial Activity of Romanian Propolis against Staphylococcus aureus Isolated from Dogs with Superficial Pyoderma: In Vitro Test

Veterinary Sciences, 2022
Staphylococcal infection treatment in dogs is frequently associated with adverse side effects, high costs, prolonged treatment, and resistant strain selection.
János Dégi, Viorel Herman, Violeta Igna, Diana Maria Dégi, Anca Hulea, Florin Muselin, Romeo Teodor Cristina   +6 more
doaj   +1 more source

Food-Borne Transmission of Staphylococci

, 2018
Staphylococcal food poisoning (SFP) is widespread worldwide, but it is frequently underreported because the illness is relatively mild. Control strategies are complicated by the fact that enterotoxin-producing staphylococci do not always share the same ...
Antonello Paparella, Chiara Rossi, Mazzarrino, Giovanni, Giovanni Mazzarrino, Annalisa Serio, Paparella, Antonello, Clemencia Chaves López, Rossi, Chiara, Serio, Annalisa, Chaves López, Clemencia   +9 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Wearable Smart Patches on Sustainable Chitosan With Reversible Microbial Growth‐Inhibitory Properties

Advanced Functional Materials, EarlyView.
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti, Kubra Kocak, Andrea Michel, Enrico Cavarzerani, Ali Raza, Petr Rohzin, Nouha Loudhaief, Saimir Frroku, Nicolò Baldovin, Hazrat Bilal, Alvise Perosa, Maurizio Selva, Flavio Rizzolio, Luca Sbuelz, Sabrina Tamburini, Domenico De Fazio, Giovanni Antonio Salvatore   +16 more
wiley   +1 more source

Risk of cardiac pacemaker pocket infection in a tertiary care hospital

Indian Journal of Pathology and Microbiology, 2017
Background: The risk of pacemaker pocket infections (PPIs) is rare with good antisepsis techniques and use of advanced antibiotics. However, injudicious antibiotic usage leads to the rise of multidrug-resistant bacteria, which may cause PPI.
Jaswinder Singh Gill, Navreet Singh, S P Khanna   +2 more
doaj   +1 more source