Results 71 to 80 of about 1,280,207 (394)
Homology of mecA gene in methicillin-resistant Staphylococcus haemolyticus and Staphylococcus simulans to that of Staphylococcus aureus [PDF]
Antimicrobial Agents and Chemotherapy, 1990 A penicillin-binding protein of molecular weight 76,000 inducible by beta-lactams was detected in methicillin-resistant Staphylococcus haemolyticus and Staphylococcus simulans. DNA from these strains hybridized to the mecA gene from Staphylococcus aureus; however, the chromosomal HindIII fragments containing the mecA genes were 3.4 kilobases in S ...
Kimiko Ubukata +4 more
openaire +3 more sources
Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]
, 2016 Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Infection and Drug Resistance, 2021 Dimshasha Tolera Dabele,1 Bizunesh Mideksa Borena Snr,2 Petros Admasu,2 Endrias Zewdu Gebremedhin,2 Lencho Megersa Marami3 1Asella Regional Veterinary Laboratory, Asella, Oromia Regional State, Ethiopia; 2Department of Veterinary Science, Ambo University,
Dabele DT +4 more
doaj
Regulatory Mechanisms in Biosystems, 2017 Dysbiotic disorders, realized as changes in the composition of microbiota of different biotopes, are among the most difficult conditions to cure. This is due primarily to the fact that opportunistic microorganisms that actually mediate the development of
T. M. Shevchenko +3 more
doaj +1 more source
Staphylococcus aureus Secreted Toxins and Extracellular Enzymes
Microbiology spectrum, 2019 Staphylococcus aureus is a formidable pathogen capable of causing infections in different sites of the body in a variety of vertebrate animals, including humans and livestock. A major contribution to the success of S. aureus as a pathogen is the plethora
K. Tam, V. Torres
semanticscholar +1 more source
Staphylococcus epidermidis—Skin friend or foe?
PLoS Pathogens, 2020 Author summary Our skin is our first line of defense against environmental and pathogenic challenges. It is densely populated by a flora of bacteria, fungi, and viruses that normally interact with each other and with our immune system to promote skin ...
Morgan M Brown, A. Horswill
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao +9 more
wiley +1 more source
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]
, 2020 Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A +5 more
core +3 more sources
The Continuing Threat of Methicillin-Resistant Staphylococcus aureus
Antibiotics, 2019 Staphylococcus aureus has been an exceptionally successful pathogen, which is still relevant in modern age-medicine due to its adaptability and tenacity.
M. Gajdács
semanticscholar +1 more source