Results 101 to 110 of about 24,475 (286)

The core phageome and its interrelationship with preterm human milk lipids

Cell Reports, 2023
Summary: Phages and lipids in human milk (HM) may benefit preterm infant health by preventing gastrointestinal pathobiont overgrowth and microbiome modulation. Lipid association may promote vertical transmission of phages to the infant.
Wen C. Yew, Gregory R. Young, Andrew Nelson, William Cheung, Christopher J. Stewart, Simon H. Bridge, Claire Granger, Janet E. Berrington, Nicholas D. Embleton, Darren L. Smith   +9 more
doaj  

Overcoming Toxicity Barriers for Boosting Nisin Synthesis in Lactococcus lactis Strain via Adaptive Laboratory Evolution

Food Chemistry International, EarlyView.
After adaptive laboratory evolution against nisin, improved nisin production and tolerance were found in the evolved strains. To reveal the advantages of the evolved strains, a systematic comparison was made between the starting strains and the domesticated strains in terms of their microscopic morphology, metabolomics, transcriptomics, and whole ...
Xinyue Liu, Yuwei Sun, Jiang Zhu, Fang Wang, Zhijia Liu, Yanfei Wang, Shengbao Cai, Junjie Yi   +7 more
wiley   +1 more source

Genomic characterization of two Staphylococcus epidermidis bacteriophages with anti-biofilm potential

BMC Genomics, 2012
Background Staphylococcus epidermidis is a commensal bacterium but can colonize the hospital environment due to its ability to form biofilms favouring adhesion to host tissues, medical devices and increasing resistance to antibiotics.
Gutiérrez Diana, Martínez Beatriz, Rodríguez Ana, García Pilar   +3 more
doaj   +1 more source

Dysbiosis of gut microbiota in COVID-19 is associated with intestinal DNA phage dynamics of lysogenic and lytic infection. [PDF]

Microbiol Spectr
This study compared intestinal DNA phage dynamics and gut microbiota changes observed at the onset of coronavirus disease 2019 (COVID-19). The study participants included 19 healthy individuals and 19 patients with severe acute respiratory syndrome ...
Ishizaka A, Tamura A, Koga M, Mizutani T, Yamayoshi S, Iwatsuki-Horimoto K, Yasuhara A, Yamamoto S, Nagai H, Adachi E, Suzuki Y, Kawaoka Y, Yotsuyanagi H.   +12 more
europepmc   +2 more sources

Experimental phage therapy of burn wound infection : difficult first steps [PDF]

, 2014
Antibiotic resistance has become a major public health problem and the antibiotics pipeline is running dry. Bacteriophages (phages) may offer an ‘innovative’ means of infection treatment, which can be combined or alternated with antibiotic therapy and ...
De Vos, Daniel, Jennes, Serge, Lavigne, Rob, Merabishvili, Maia, Pirnay, Jean Paul, Rose, Thomas, Vaneechoutte, Mario, Verbeken, Gilbert, Zizi, Martin   +8 more
core  

Novel phages of healthy skin metaviromes from South Africa [PDF]

, 2018
Recent skin metagenomic studies have investigated the harbored viral diversity and its possible influence on healthy skin microbial populations, and tried to establish global patterns of skin-phage evolution.
A Cazares, A Pawluk, AK DeGruttola, AL McGuire, AM Comeau, BD Ondov, BS Weber, D Bryan, D Gutiérrez, D Gutiérrez, D Paez-Espino, D Willner, DE Dutilh, DT Pride, EM Adriaenssens, G Gloor, G Lallo Di, G Vaidya, GD Hannigan, GD Hannigan, GD Hannigan, I Grissa, J Bondy-Denomy, J Oh, JA Sanford, JR Zaneveld, JT Staley, JT Trinh, K Cadwell, K Nakayama, K Savijoki, K Tamura, KH Lynch, KH Schleifer, KH To, KR Clarke, KRT Chng, L Dziewit, L Latino, LA Ogilvie, LDR Melo, M Breitbart, M Deghorain, M Harker, M Naidu, M Rajaure, M Varga, MC Hansen, MHY Leung, MJ Sullivan, MRJ Clokie, NA Andreani, NB Pincus, NV Ravin, P Columpsi, P Peduzzi, Q Shao, Q Sun, R Lavigne, R Robles-Sikisaka, S Hayes, S Minot, S Roux, S Roux, SR Abeles, SR Casjens, T Bae, TN Mavrich, V Foulongne, W Demczuk, Y Zhang, Y Zhou, Z Cui, Z Liu   +73 more
core   +1 more source

Construction of Reporter Phage T4::Nluc and Its Application in the Detection of Escherichia coli in Urinary Tract Infections

iLABMED, EarlyView.
A reporter phage T4::Nluc was constructed using the CRISPR/Cas9 system combined with homologous recombination and was applied for the detection of clinical Escherichia coli in urinary tract infections (UTIs). T4::Nluc exhibited superior sensitivity and specificity, and had a short detection time, making it a powerful tool for diagnosing UTIs.
Zhiyun Hao, Minwei Li, Qiang Zhao, Liye Wang, Ting Liu, Chi Wang, Chengbin Wang   +6 more
wiley   +1 more source

The impact of simultaneous infections on phage-host ecology [PDF]

Phages use bacterial host resources to replicate, intrinsically linking phage and host survival. To understand phage dynamics, it is essential to understand phage-host ecology. A key step in this ecology is infection of bacterial hosts. Previous work has explored single and multiple, sequential infections.
arxiv   +1 more source

Sustainable Diversity of Phage-Bacteria Systems [PDF]

arXiv, 2023
Bacteriophages are central to microbial ecosystems for balancing bacterial populations and promoting evolution by applying strong selection pressure. Here we review some of the known aspects that modulate phage-bacteria interaction in a way that naturally promotes their coexistence.
arxiv  

Skin microbiome engineering: Challenges and opportunities in skin diseases treatment

iMetaOmics, EarlyView.
The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley   +1 more source