Results 111 to 120 of about 24,475 (286)

N-TERMINAL PROCESSING OF RIBOSOMAL PROTEIN L27 IN STAPHYLOCOCCUS AUREUS [PDF]

, 2012
The bacterial ribosome is essential to cell growth yet little is known about how its proteins attain their mature structures. Recent studies indicate that certain Staphlyococcus aureus bacteriophage protein sequences contain specific sites that may be ...
Caufield, J. Harry
core   +1 more source

Anti‐Pseudomonas Aeruginosa Bacteriophage Loaded Electrospun Fibers for Antibacterial Wound Dressings

Macromolecular Rapid Communications, EarlyView.
Multidrug resistant Pseudomonas (P.) aeruginosa is detected in many infected wounds and is challenging to treat with antibiotics. As an alternative, this work incorporates anti‐P. aeruginosa Neko phages into electrospun fibres to explore their potential for treating infected wounds.
Tian Ju, Jixuan Li, Andrew Weston, Giovanni Satta, Sara Bolognini, Mariagrazia Di Luca, Simon Gaisford, Gareth R. Williams   +7 more
wiley   +1 more source

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

Mass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Landscape phage, phage display, stripped phage, biosensors, detection, affinity reagent, nanotechnology, Salmonella typhimurium, Bacillus anthracis [PDF]

Dans European Nano Systems Worshop - ENS 2005, Paris : France (2005), 2007
Filamentous phage, such as fd used in this study, are thread-shaped bacterial viruses. Their outer coat is a tube formed by thousands equal copies of the major coat protein pVIII. We constructed libraries of random peptides fused to all pVIII domains and selected phages that act as probes specific for a panel of test antigens and biological threat ...
arxiv  

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Novel applications of shotgun phage display [PDF]

, 2004
In a shotgun phage display library, theoretically, the entire proteome of a bacterium is represented. Phages displaying specific polypeptides can be isolated by affinity selection, while the corresponding gene remains physically linked to the gene ...
Rosander, Anna
core  

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Molecular aspects and comparative genomics of bacteriophage endolysins [PDF]

, 2013
Phages are recognized as the most abundant and diverse entities on the planet. Their diversity is predominantly determined by their dynamic adaptation capacities, when confronted with different selective pressures in an endless cycle of co-evolution with
Azeredo, Joana, Cerca, Nuno, Ferreira, E. C., Kluskens, Leon, Melo, Luís D. R., Nóbrega, Franklin Luzia, Oliveira, Hugo Alexandre Mendes, Santos, Sílvio Roberto Branco   +7 more
core   +1 more source

Design Principles of Nanosensors for Multiplex Detection of Contaminants in Food

Small, EarlyView.
This review discusses recent advancements in nanoparticle‐based nanosensors for multiplex detection of food contaminants, focusing on toxins and pathogens. It highlights the design principles, sensitivity, and selectivity of these sensors, offering insights into their practical applications for food safety monitoring and inspiring future innovations ...
Yang Zhang, Shipeng Gao, Haoran Li, Tianxi Yang, Kaiyi Zheng, Zhing Ming Guo, Jiyong Shi, Xiaowei Huang, Xiaobo Zou, Pierre Picchetti, Frank Biedermann   +10 more
wiley   +1 more source

Potential of training of anti-Staphylococcus aureus therapeutic phages against Staphylococcus epidermidis multidrug-resistant isolates is restricted by inter- and intra-sequence type specificity

mSystems
Phage therapy appears to be a promising approach to tackle multidrug-resistant bacteria, including staphylococci. However, most anti-staphylococcal phages have been characterized in Staphylococcus aureus, while a limited number of studies investigated ...
Camille Kolenda, Mélanie Bonhomme, Mathieu Medina, Mateo Pouilly, Clara Rousseau, Emma Troesch, Patricia Martins-Simoes, Marc Stegger, Paul O. Verhoeven, Floriane Laumay, Frédéric Laurent   +10 more
doaj   +1 more source