Results 131 to 140 of about 24,475 (286)

Clustering Zwitterionic Amino Acids at the Upper Rim of Cone Calix[4]arene Triggers the Selective Recognition of Gram‐Negative Bacterial Envelope

Small Structures, EarlyView.
By Saturation Transfer Difference Nuclear Magnetic Resonance studies, calix[4]arenes bearing zwitterionic amino acids are identified as selective ligands for Gram‐negatives over Gram‐positives or mycobacteria, suggesting them as promising ligands for the detection and targeting of this class of bacteria.
Francesco Rispoli, Luca Moretti, Carlo Alberto Vezzoni, Eloisa Tosi, Linda Molteni, Carlotta Ciaramelli, Luciano Marchiò, Stefano Volpi, Laura Baldini, Francesco Sansone, Alessandro Palmioli, Cristina Airoldi, Alessandro Casnati   +12 more
wiley   +1 more source

Analysis of Different Parameters Affecting Diffusion, Propagation and Survival of Staphylophages in Bacterial Biofilms

Frontiers in Microbiology, 2018
The elimination of bacterial biofilms remains a major challenge due to their recalcitrant nature. Bacteriophages, viruses that infect bacteria, have been gaining increasing attention as biofilm control agents.
Silvia González, Lucía Fernández, Diana Gutiérrez, Ana Belén Campelo, Ana Rodríguez, Pilar García   +5 more
doaj   +1 more source

Phage Multiplication on Two Hosts. Isolation and Activity of Variants of Staphylococcus Phage P1

Experimental Biology and Medicine, 1952
SummaryAnalysis of phage activity by titration on two hosts has revealed the presence of variants hitherto undetected in stock phage P1. One isolate, Phage 14, exhibits great changes in titration ratio on passage through the two hosts K1 and WF 145. Produced on K1 cells, the ratio of free phage assayed on two hosts is 1.3, whereas made on 145 cells ...
Albert P. Krueger, Doris J. Ralston
openaire   +3 more sources

Lytic Transglycosylase Deficiency Increases Susceptibility to β‐lactam Antibiotics But Reduces Susceptibility to Vancomycin in Escherichia coli

Microbiology and Immunology, EarlyView.
ABSTRACT In Staphylococcus aureus, a gram‐positive pathogen, vancomycin‐resistant strains become susceptible to β‐lactam antibiotics, referred to as the “seesaw effect.” However, in gram‐negative bacteria, the phenomenon is less clear. Here, we analyzed the gene‐knockout effects of eight lytic transglycosylases (slt, mltA, mltB, mltC, mltD, mltE, mltF,
Takahiko Kimura, Kazuya Ishikawa, Ryosuke Nakagawa, Kazuyuki Furuta, Chikara Kaito   +4 more
wiley   +1 more source

Early Origins of Asthma and Allergies: Clues From Studies in China

Clinical &Experimental Allergy, EarlyView.
The environment we live in harbours both risk and protective factors for asthma and allergies. This is particularly relevant in China, where unique environmental and cultural factors shape disease development. The interplay between these environmental factors, airway immunity, and gut microbiome shapes the susceptibility to asthma and allergies ...
Yike Wang, Jing Yang, Xueling Lai, Agnes Sze‐Yin Leung, Yuhan Xing, Gary Wing‐Kin Wong   +5 more
wiley   +1 more source

Prime Editing: A Revolutionary Technology for Precise Treatment of Genetic Disorders

Cell Proliferation, Volume 58, Issue 4, April 2025.
This review outlines the latest research advancements in prime editing technology, delivery strategies, and the challenges that must be addressed to fully realize its therapeutic potential, emphasizing the high potential of prime editing in the remission or cure of genetic diseases. ABSTRACT Genetic diseases have long posed significant challenges, with
Mengyao Li, Yi Lin, Qiang Cheng, Tuo Wei
wiley   +1 more source

Effects of prophylactic administration of bacteriophages to immunosuppressed mice infected with Staphylococcus aureus

BMC Microbiology, 2009
Background Bacteriophages can be successfully applied to treat infections caused by antibiotic-resistant bacteria. Until now no attempts have been undertaken to treat infections in immunosuppressed patients with phages.
Borysowski Jan, Weber-Dąbrowska Beata, Kocięba Maja, Artym Jolanta, Zimecki Michał, Górski Andrzej   +5 more
doaj   +1 more source

The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives [PDF]

, 2014
Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a ...
Todd, Kelly
core   +2 more sources

Molecular Characterisation of Bacteriophage K Towards Applications for the Biocontrol of Pathogenic Staphylococci [PDF]

, 2006
End of project reportThe aim of this work was to characterise staphylococcal bacteriophage (a bacterial virus) and to assess their potential as therapeutic agents against pathogenic strains of Staphylococcus aureus, particularly mastitis-causing strains.
Coffey, Aidan, Fitzgerald, Gerald F, Flynn, James, Meaney, William J, O'Flaherty, Sarah, Ross, R Paul   +5 more
core  

Characterization of Staphylococcus epidermidis phage vB_SepS_SEP9 : a unique member of the Siphoviridae family [PDF]

, 2014
Relatively few phages (
Ackermann, Altschul, Altschul, Andrew M. Kropinski, Aziz, Bailey, Benson, Birkeland, Casjens, Cavalli-Sforza, Ceyssens, Daniel, Deghorain, Deghorain, Dereeper, Donovan, Garcia, Gutierrez, Gutierrez, Gutierrez, Hans-Wolfgang Ackermann, Hargreaves, Hatfull, Hughes, Joana Azeredo, Kall, Kall, Katsura, King, Kropinski, Kwan, Laslett, Lavigne, Lavigne, Lobocka, Loc-Carrillo, Luzzaro, Luís D.R. Melo, Madhusoodanan, Mayer, Melo, Naville, Nuno Cerca, Oliveira, Otto, Otto, Riipinen, Sanna Sillankorva, Schattner, Sillankorva, Soding, Sulakvelidze, Tavares, Walker, Wang, Wilkins, Zuker   +56 more
core   +1 more source