Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]
Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A+5 more
core +3 more sources
Methods for eradication of the biofilms formed by opportunistic pathogens using novel techniques – A review [PDF]
The inconvenient environmental conditions force microorganisms to colonize either abiotic surfaces or animal and plant tissues and, therefore, form more resistant structures – biofilms.
Kunicka-Styczyńska, Alina+2 more
core +1 more source
As a primary bacterial pathogen in companion animals, Staphylococcus pseudintermedius has zoonotic potential. This pathogen exhibits multidrug resistance, including resistance to methicillin, and biofilm-forming ability, making it hard to eradicate with ...
Sang Guen Kim+9 more
doaj +1 more source
Biological properties of Staphylococcus virus ΦSA012 for phage therapy
AbstractStaphylococcus virus ΦSA012 has a wide host range and efficient lytic activity. Here, we assessed the biological stability of ΦSA012 against temperature, freeze-thawing, and pH to clinically apply the phage. In addition, inoculation of ΦSA012 through i.p. and i.v.
Jumpei Fujiki+19 more
openaire +3 more sources
Phages and human health: More than idle hitchhikers [PDF]
Bacteriophages, or phages, are viruses that infect bacteria and archaea. Phages have diverse morphologies and can be coded in DNA or RNA and as single or double strands with a large range of genome sizes. With the increasing use of metagenomic sequencing
Baldridge, Megan T+2 more
core +2 more sources
The Influence of Acridines on the Interaction of Staphylococcus aureus and Staphylococcus K phage [PDF]
SUMMARY: The inhibition of multiplication of staphylococcus K bacteriophage by six acridines and two amidines has been studied using mass lysis and one-step growth curve techniques. The effect of the different inhibitors upon the growth rate of the organisms was found to vary from below 5 to 100% inhibition at a concentration sufficient to double lysis-
openaire +3 more sources
EFFECT OF SODIUM CHLORIDE ON STAPHYLOCOCCUS-PHAGE RELATIONSHIPS [PDF]
West, B. (University of Oklahoma Medical Center, Oklahoma City),Florene C. Kelly, and Doris A. Shields. Effect of sodium chloride on staphylococcus-phage relationships. J. Bacteriol.86:773–780. 1963.—Phage patterns of 21 phage-propagating strains of staphylococci on medium with high NaCl content appeared to be an expression of the staphylococcal cells,
Doris A. Shields+2 more
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Biomimetic hydroxyapatite nanocrystals are an active carrier for Salmonella bacteriophages [PDF]
open access articlePurpose: The use of bacteriophages represents a valid alternative to conventional antimicrobial treatments, overcoming the widespread bacterial antibiotic resistance phenomenon.
Capparelli, Rosanna+12 more
core +2 more sources
Plasmids of phage-group-II Staphylococcus aureus [PDF]
Most phage-Group-II Staphylococcus aureus have been shown to carry at least one plasmid. The proportion of strains that are resistant to tetracycline appears to have increased during the last 17 years. Restriction maps of several of the small plasmids isolated from Group-II strains are presented and compared with those known for staphylococcal plasmids.
K. G. H. Dyke, W. C. Noble
openaire +3 more sources
Deciphering the Genetic Architecture of Staphylococcus warneri Prophage vB_G30_01: A Comprehensive Molecular Analysis. [PDF]
The current knowledge of Staphylococcus warneri phages is limited, with few genomes sequenced and characterized. In this study, a prophage, vB_G30_01, isolated from Staphylococcus warneri G30 was characterized and evaluated for its lysogenic host range ...
Pu F+6 more
europepmc +2 more sources