Results 81 to 90 of about 463,138 (331)

Methods for eradication of the biofilms formed by opportunistic pathogens using novel techniques – A review [PDF]

, 2016
The inconvenient environmental conditions force microorganisms to colonize either abiotic surfaces or animal and plant tissues and, therefore, form more resistant structures – biofilms.
Kunicka-Styczyńska, Alina, Tyfa, Agnieszka, Zabielska, Julia   +2 more
core   +1 more source

Pro- and anti-inflammatory responses of peripheral blood mononuclear cells induced by Staphylococcus aureus and Pseudomonas aeruginosa phages

Scientific Reports, 2017
The ability of bacteriophages to kill bacteria is well known, as is their potential use as alternatives to antibiotics. As such, bacteriophages reach high doses locally through infection of their bacterial host in the human body.
Jonas D. Van Belleghem, F. Clement, M. Merabishvili, R. Lavigne, Mario Vaneechoutte   +4 more
semanticscholar   +1 more source

Phage activity against Staphylococcus aureus is impaired in plasma and synovial fluid

bioRxiv, 2023
S. aureus is a pathogen that frequently causes severe morbidity and phage therapy is being discussed as an alternative to antibiotics for the treatment of S. aureus infections.
Michele Mutti, D. Moreno, Marcela Restrepo-Córdoba, Zehra Visram, G. Resch, L. Corsini   +5 more
semanticscholar   +1 more source

3D Printing of Bacteriophage‐Loaded Hydrogels: Development of a Local and Long‐Lasting Delivery System

Advanced Healthcare Materials, EarlyView.
This research investigates the feasibility of 3D‐printing of a bacteriophage‐containing hydrogel made of alginate and methylcellulose. The printed hydrogels steadily release active bacteriophages for up to 35 days which is beneficial to treat implant‐associated infections.
Corina Vater, Gopala Krishna Mannala, Max von Witzleben, Richard Frank Richter, Nike Walter, Michael Gelinsky, Volker Alt, Anja Lode, Markus Rupp   +8 more
wiley   +1 more source

New Genus Fibralongavirus in Siphoviridae Phages of Staphylococcus pseudintermedius

Viruses, 2019
Bacteriophages of the significant veterinary pathogen Staphylococcus pseudintermedius are rarely described morphologically and genomically in detail, and mostly include phages of the Siphoviridae family.
Michal Zeman, P. Bárdy, V. Vrbovská, Pavel Roudnický, Z. Zdráhal, V. Růžičková, J. Doškař, R. Pantůček   +7 more
semanticscholar   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Bacteriophages from human skin infecting coagulase-negative Staphylococcus: diversity, novelty and host resistance

Scientific Reports
The human skin microbiome comprises diverse populations that differ temporally between body sites and individuals. The virome is a less studied component of the skin microbiome and the study of bacteriophages is required to increase knowledge of the ...
Samah E. Alsaadi, Hanshuo Lu, Minxing Zhang, Gregory F. Dykes, Heather E. Allison, Malcolm J. Horsburgh   +5 more
doaj   +1 more source

Phage Therapy for Orthopaedic Infections: The First Three Cases from the United Kingdom

Antibiotics
Background: Bacteriophages (phages) are viruses that infect and kill bacteria. The antimicrobial resistance crisis has driven renewed interest in phage therapy, including the use of phages to treat chronic orthopaedic infections.
Daniela I. Munteanu, John Dunn, Gábor Apjok, Bálint Kintses, Johann Griselain, Griet Steurs, Christel Cochez, Sarah Djebara, Maya Merabishvili, Jean-Paul Pirnay, Vida Štilec, Matjaž Peterka, Emily A. Simpson, Samantha Downie, Alasdair MacInnes, Graeme Nicol, Benedict Clift, Joshua D. Jones   +17 more
doaj   +1 more source

Analysis of phage resistance in Staphylococcus aureus SA003 reveals different binding mechanisms for the closely related Twort-like phages ɸSA012 and ɸSA039

Applied Microbiology and Biotechnology, 2018
We have previously generated strains of Staphylococcus aureus SA003 resistant to its specific phage ɸSA012 through a long-term coevolution experiment. However, the DNA mutations responsible for the phenotypic change of phage resistance are unknown. Whole-
A. Azam, Fumiya Hoshiga, Ippei Takeuchi, K. Miyanaga, Y. Tanji   +4 more
semanticscholar   +1 more source

Treatment with Plasma Activated (Salt) Water Sterilizes Macromolecular Coatings While Maintaining Their Integrity and Functionality

Advanced Materials Interfaces, EarlyView.
PDMS samples were covalently coated with mucin glycoproteins and then treated with either plasma activated water (PAW) or saline (PAS) as a means of disinfection. The samples could be successfully sterilized without compromising the structural integrity or functionality of those coatings.
Bernardo Miller Naranjo, Markus Ahrens, Ádám Nemes, Petra Mela, Oliver Lieleg   +4 more
wiley   +1 more source