Results 131 to 140 of about 45,046 (289)
HD 7977 and its possible influence on Solar System bodies [PDF]
Context. In the latest Gaia third data release, one can find extremely small proper motion components for the star HD 7977. This, together with the radial velocity measurement lead to the conclusion that this star passed very close to the Sun in the ...
de Bruijne, Jos +16 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Celluloid Bodies: Images of Intellectuals in Film
, 2000 This chapter examines the image of intellectuals in film. Films mentioned include Lolita, The Browning Version, Star Trek Next Generation, No Regrets for our Youth, Providence, Mon Oncle d ...
O'Farrell, Clare D.
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Formation of Double Hot Jupiter Systems through von Zeipel–Lidov–Kozai Migration
The Astrophysical JournalThe von Zeipel–Lidov–Kozai (ZLK) mechanism with tidal friction has been demonstrated as a promising avenue to generate hot Jupiters in stellar binary systems.
Yurou Liu, Tiger Lu, Malena Rice
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Isoperimetric-type Inequalities for g-chordal Star-shaped Sets in Rn [PDF]
, 2017 This paper generalizes certain existing isoperimetric-type inequalities from R2 to higher dimensions. These inequalities provide lower bounds for the n-dimensional volume and, respectively, surface area of certain star-shaped bodies in Rn and ...
Abbas, Zahraa
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 1974 A star scanner on a spin stabilized spacecraft is described which includes a reticle with a pair of slits having different separations as a function of the spacecraft vertical plane, to form a V slit.
Gutshall, R. L. +2 more
core
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source