Results 111 to 120 of about 24,866 (298)

The S-PLUS Fornax Project (S+FP): An extragalactic catalog covering ∼5 virial radii around NGC1399 with galaxy properties

Astronomy & Astrophysics
Context. Observational extragalactic catalogs over wide sky areas are essential for uncovering the large-scale structure of the Universe. They allow, among other things, cosmological studies and density analyses that impose strong constraints on models ...
Haack R. F., Smith Castelli A. V., Sodré L., Mendes de Oliveira C., Lopes A. R., Gutiérrez-Soto L. A., Demarco R., Olave-Rojas D. E., Carrasco E. R., Humire P. K., Calderón J. P., de Almeida Fernandes F., Lomelí-Núñez L., Sepúlveda G., Lima-Dias C., Torres Flores S., Telles E., Cardoso N. M., Palma D., Doubrawa L., Pallero D., Marinello M., Schoenell W., Ribeiro T., Kanaan A.   +24 more
doaj   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Young Stellar Objects in the Carina Nebula: Near-infrared Variability and Spectroscopy

The Astronomical Journal
We present a catalog of 652 young stellar objects (YSOs) in the Carina star-forming region. The catalog was constructed by combining near-infrared K _S -band variability from the VISTA Variables in the Vía Láctea eXtended survey and medium-resolution H ...
Jura Borissova, Radostin Kurtev, Josemanuel Escobar, Javier Alonso-García, Nicolas Medina, Javier Osses, Zhen Guo, Philip W. Lucas, Michael Kuhn, Dante Minniti, Kevin R. Covey, Roberto K. Saito, Francisco Förster   +12 more
doaj   +1 more source

The 1980-90 shuttle star catalog for onboard and ground programs

, 1978
The 1980-90 shuttle star catalog for onboard and ground programs is presented. The data used in this catalog are explained according to derivation, input, format for the catalog, and preparation.
Richardson, S., Killen, R.
core  

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Washington Double Star Catalog Cross Index (1950 position sort)

, 1993
A machine-readable version of the Washington Catalog of Visual Double Stars (WDS) was prepared in 1984 on the basis of a data file that was collected and maintained for more than a century by a succession of double-star observers.

core  

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

JWST Observations of Starbursts: Massive Star Clusters in the Central Starburst of M82

The Astrophysical Journal Letters
We present a near-infrared (NIR) candidate star cluster catalog for the central kiloparsec of M82 based on new JWST NIRCam images. We identify star cluster candidates using the F250M filter, finding 1357 star cluster candidates with stellar masses >10 ^4
Rebecca C. Levy, Alberto D. Bolatto, Divakara Mayya, Bolivia Cuevas-Otahola, Elizabeth Tarantino, Martha L. Boyer, Leindert A. Boogaard, Torsten Böker, Serena A. Cronin, Daniel A. Dale, Keaton Donaghue, Kimberly L. Emig, Deanne B. Fisher, Simon C. O. Glover, Rodrigo Herrera-Camus, María J. Jiménez-Donaire, Ralf S. Klessen, Laura Lenkić, Adam K. Leroy, Ilse De Looze, David S. Meier, Elisabeth A. C. Mills, Juergen Ott, Mónica Relaño, Sylvain Veilleux, Vicente Villanueva, Fabian Walter, Paul P. van der Werf   +27 more
doaj   +1 more source

Mathematical Problems in Creating Large Astronomical Catalogs

Open Astronomy, 2016
The next stage after performing observations and their primary reduction is to transform the set of observations into a catalog. To this end, objects that are irrelevant to the catalog should be excluded from observations and gross errors should be ...
Prokhorov M. E., Zakharov A. I., Kroussanova N. L., Tuchin M. S., Kortunov P. V.   +4 more
doaj   +1 more source