Results 121 to 130 of about 24,866 (298)

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Development of Experimental Star Sensor for LAPAN-A3/IPB Microsatellite

, 2016
LAPAN-A3/IPB is an Indonesian microsatellite, which has a main mission of remote sensing using multispectral pushbroom imager and global maritime traffic monitoring using Automatic Identification System (AIS).
Deddy El Amin, M. Arif Saifudin, Mohammad Farid Huzain   +2 more
core  

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

Large-scale Structures in COSMOS2020: Evolution of Star Formation Activity in Different Environments at 0.4 < z < 4

The Astrophysical Journal
To study the role of environment in galaxy evolution, we reconstruct the underlying density field of galaxies based on COSMOS2020 (The Farmer catalog) and provide the density catalog for a magnitude-limited ( K _s < 24.5) sample of ∼210,000 galaxies at 0.
Sina Taamoli, Bahram Mobasher, Nima Chartab, Behnam Darvish, John R. Weaver, Shoubaneh Hemmati, Caitlin M. Casey, Zahra Sattari, Gabriel Brammer, Peter L. Capak, Olivier Ilbert, Jeyhan S. Kartaltepe, Henry J. McCracken, Andrea Moneti, David B. Sanders, Nicholas Scoville, Charles L. Steinhardt, Sune Toft   +17 more
doaj   +1 more source

Analysis of Star Catalog Model Based on The Nearest Star Composition and Brightest Star as Guide Star

Star sensor is the most advanced attitude determining instrument for spacecraft with very high accuracy, and it is independent of other attitude sensors.
Ramadhana, Alif, Fathurahim, L, Poetro, Ridanto E, Saifudin, M A   +3 more
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

The Dark Energy Survey Six-Year Calibration Star Catalog

, 2023
International audienceThis Technical Note presents a catalog of calibrated reference stars that was generated by the Forward Calibration Method (FGCM) pipeline (arXiv:1706.01542) as part of the FGCM photometric calibration of the full Dark Energy Survey (
Annis, J, de Vicente, J, Wiseman, P, Allam, S.S, Frieman, J, Palmese, A, García-Bellido, J, Nord, B.D, Lasker, J, Brout, D, Vincenzi, M, Schubnell, M, Hinton, S.R, Andrade-Oliveira, F, Weaverdyck, N, Gruen, D, James, D.J, Kuehn, K, Castander, F.J, Bechtol, K, Bacon, D, Santiago, B, Bertin, E, Menanteau, F, Mena-Fernández, J, Suchyta, E, Alves, O, Rosell, A. Carnero, Sanchez, E, Rykoff, E.S, Tucker, D.L, Carretero, J, Soares-Santos, M, Smith, J.A, Swanson, M.E.C, Walker, A.R, Varga, T.N, Pereira, M.E.S, Choi, A, da Costa, L.N, Marshall, J.L, Myles, J, Brooks, D, Doel, P, Giannini, G, Bernstein, G.M, Burke, D.L, Abbott, T.M.C, Davis, T.M, Smith, M, Yanny, B, Hollowood, D.L, Ogando, R.L.C, Ferrero, I, Malagón, A.A. Plazas, Rodgríguez-Monroy, M, Lahav, O, Raveri, M, Gutierrez, G, Wester, W.C, Diehl, H.T, Gruendl, R.A, Aguena, M, Sevilla-Noarbe, I, Pieres, A, Everett, S, Drlica-Wagner, A   +66 more
core   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Catalog of Outbursts of Neutron Star Low-mass X-Ray Binaries

The Astrophysical Journal Supplement Series
Many X-ray binaries (XRBs) are transiently accreting. Having statistics on their recurrence times is helpful to address questions related to binary evolution and populations, as well as the physics of binary systems.
Craig O. Heinke, Junwen Zheng, Thomas J. Maccarone, Nathalie Degenaar, Arash Bahramian, Gregory R. Sivakoff, Simrat Toor   +6 more
doaj   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source