Results 161 to 170 of about 4,162,760 (300)
Advanced Science, EarlyView.Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng +8 more
wiley +1 more source
Massively Parallel In Vitro Functional Analysis of Evolution-Derived Transcriptional Riboswitch Sequences. [PDF]
Bio ProtocHertz LM, Lucks JB.
europepmc +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
Advanced Science, EarlyView.By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
Machine learning-enabled membership determination of open cluster AH03_J0748-26.9 using Gaia DR3 astrometry. [PDF]
Sci RepBadawy WA, Abdel Rahman HI.
europepmc +1 more source
Advanced Science, EarlyView.Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu +12 more
wiley +1 more source
Protocol for manipulating mRNA splicing via vivo-morpholino in early-activating muscle stem cells. [PDF]
STAR ProtocLin K, Yin Y, Cheung TH.
europepmc +1 more source