Results 41 to 50 of about 24,866 (298)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Prototype Development of the Star Sensor for the KITSAT-3 [PDF]
Journal of Astronomy and Space Sciences, 1995 This report presents the development procedure and the results of a prototype star sensor which can be sued as one of the attitude sensors of the KITSAT-3.
Hyunwoo Lee +3 more
doaj
A Catalog of Stars Observed Simultaneously by Kepler and TESS [PDF]
Research Notes of the AAS, 2018 Published as a RNAAS, this version includes an additional figure not in the research note.
Thomas Barclay, Geert Barentsen
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
GENERAL CATALOGUE OF VARIABLE STARS: CURRENT STATUS AND NEW NAME-LISTS
Odessa Astronomical Publications, 2010 A short history of variable-star catalogs is presented. After the second World War, the International Astronomical Union asked astronomers of the Soviet Union to become responsible for variable-star catalogs. Currently, the catalog is kept electronically
N. N. Samus +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Catalog of spectrophotometric scans of stars. [PDF]
The Astrophysical Journal Supplement Series, 1976 NSF AST76-02357 ; McDonald ...
openaire +2 more sources
4-OGC: Catalog of Gravitational Waves from Compact Binary Mergers
The Astrophysical Journal, 2023 We present the fourth Open Gravitational-wave Catalog (4-OGC) of binary neutron star (BNS), binary black hole (BBH), and neutron star–black hole (NSBH) mergers.
Alexander H. Nitz +7 more
doaj +1 more source
An Investigation of the Ancient Star Catalog [PDF]
Publications of the Astronomical Society of the Pacific, 1982 Various tests are applied to Claudius Ptolemy's long-suspect claim that he himself observed the more than 1000 objects in the Ancient Star Catalog. An obvious consequence of observing under the influence of Ptolemy's large equinox-position error is found not to exist in the Catalog.
openaire +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source