Results 161 to 170 of about 91,664 (267)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Single-cell transcriptomics uncovering a critical AKT-LONP1-STAR axis in ovarian hyperandrogenism of PCOS. [PDF]

J Ovarian Res
Zhang C, Lin Z, Lin Y, Ma H.
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Integrated Analysis of Cross-Link-Ligation Data for the Detection of RNA 2D/3D Structures and Interactions In Vivo. [PDF]

Methods Mol Biol
Lee WH, Zhang M, Lu Z.
europepmc   +1 more source

Predictions for Triple Stars with and without a Pulsar in Star Clusters

, 2007
Michele Trenti, S. M. Ransom, Piet Hut, Douglas C. Heggie   +3 more
openalex   +1 more source

On black hole subsystems in idealized nuclear star clusters [PDF]

, 2013
Philip G. Breen, Douglas C. Heggie
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Dispersal Beyond Mountains and Borders: Asymmetrical Gene Flow Helps Maintain Brown Bear Metapopulation Connectivity on the Balkan Peninsula. [PDF]

Ecol Evol
Pylidis C, Matic I, Djan M, Valchev K, Ćirović D, Arangelov S, Walker S, Sarasua N, Mrazek V, Basuony AE, Bruford MW, Cuyten K, Hailer F.   +12 more
europepmc   +1 more source

In Situ Formation of Star Clusters at z > 7 via Galactic Disk Fragmentation: Shedding Light on Ultracompact Clusters and Overmassive Black Holes Seen by JWST

Lucio Mayer, Floor van Donkelaar, Matteo Messa, Pedro R. Capelo, Angela Adamo   +4 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source