Results 141 to 150 of about 440,600 (338)

Three Concurrent Phases of Massive-Star Evolution in a Pulsar-Wind Nebula [PDF]

open access: yes, 2010
The nebular material associated the the SNR G54.1+0.3 (hereafter G54) contains the the first reported instance of triggered star formation in the immediate vicinity of a Pulsar and its Wind Nebula (PWN). With 2MASS and Spitzer colors and followup near-IR
Hillier, D. John   +4 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The difficult early stages of embedded star clusters and the importance of the pre-gas expulsion virial ratio [PDF]

open access: bronze, 2015
Juan P. Farias   +6 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Ages and metallicities of five intermediate-age star clusters projected towards the Small Magellanic Cloud [PDF]

open access: bronze, 2001
Andrés E. Piatti   +5 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

On the Orbital Effects of Stellar Collisions in Galactic Nuclei: Tidal Disruption Events and Ejected Stars

open access: yesThe Astrophysical Journal Letters
Dense stellar clusters surround the supermassive black holes (SMBH) in galactic nuclei. Interactions within the cluster can alter the stellar orbits, occasionally driving a star into the SMBH’s tidal radius, where it becomes ruptured, or expelling a star
Sanaea C. Rose, Brenna Mockler
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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