Results 121 to 130 of about 98,056 (310)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Open Star Clusters and Their Asymmetrical Tidal Tails
The Astrophysical JournalStars that evaporate from their star cluster by the energy equipartition process end up in either a leading or a trailing tidal tail. In Newtonian gravitation and for open star clusters in the solar vicinity, the tidal threshold, or práh, for escape is ...
Pavel Kroupa +6 more
doaj +1 more source
Whole-sequence analysis indicates that the Y chromosome C2*-Star Cluster traces back to ordinary Mongols, rather than Genghis Khan. [PDF]
Eur J Hum Genet, 2018 Wei LH +13 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Mass Distribution of Binary Black Hole Mergers from Young and Old Dense Star Clusters
The Astrophysical JournalDense star clusters are thought to contribute significantly to the merger rates of stellar-mass binary black holes (BBHs) detected by the LIGO–Virgo–KAGRA collaboration.
Claire S. Ye +3 more
doaj +1 more source
A stochastic Monte Carlo approach to modelling real star cluster evolution -- III. Direct integration of three- and four-body interactions [PDF]
, 2003 Mirek Giersz, Rainer Spurzem
openalex +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
The Stellar Initial Mass Function of Early Dark Matter–free Gas Objects
The Astrophysical Journal LettersAmong the remarkable strides made by JWST is the discovery of the earliest star clusters found to date. These have been proposed as early progenitors of globular clusters, which are known to come from the early stages of star formation in the Universe ...
William Lake +8 more
doaj +1 more source