Results 211 to 220 of about 2,879,280 (414)
Abstract The past two decades have produced extensive evidence on the manifold and severe outcomes for victims of aggression exposure in the workplace. However, due to the dominating individual‐centered approach, most findings miss a social network perspective.
Alexander Herrmann+2 more
wiley +1 more source
Open Star Clusters and Their Asymmetrical Tidal Tails
Stars that evaporate from their star cluster by the energy equipartition process end up in either a leading or a trailing tidal tail. In Newtonian gravitation and for open star clusters in the solar vicinity, the tidal threshold, or práh, for escape is ...
Pavel Kroupa+6 more
doaj +1 more source
Energy is a major factor in designing wireless sensor networks (WSNs). In particular, in the real world, battery energy is limited; thus the effective improvement of the energy becomes the key of the routing protocols.
Yali Yuan+4 more
doaj +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Kinematic substructure in star clusters constrains star cluster formation
ABSTRACT The spatial–kinematic structure of 48 young star clusters and associations is investigated. Moran’s I statistic is used to quantify the degree of kinematic substructure in each region, and the results are compared to those expected assuming the hierarchical or monolithic models of star cluster formation. Of the observed regions,
Becky Arnold, Nicholas J Wright
openaire +2 more sources
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
UOCS XIV: Study of the Open Cluster NGC 2627 Using UVIT/AstroSat
We study the intermediate-age open cluster NGC 2627, located at a distance of ∼2 kpc, using UVIT/AstroSat and other archival data. Using a machine learning-based algorithm, ML-MOC, on the Gaia DR3 data, we identify 422 cluster members, including four ...
Pinapati Saketh+2 more
doaj +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source