Results 131 to 140 of about 2,681,556 (391)

DEPENDENCY OF DYNAMICAL EJECTIONS OF O STARS ON THE MASSES OF VERY YOUNG STAR CLUSTERS [PDF]

, 2015
Massive stars can be efficiently ejected from their birth star clusters through encounters with other massive stars. We study how the dynamical ejection fraction of O star systems varies with the masses of very young star clusters, M ecl ?> , by means of
Seungkyung Oh, P. Kroupa, J. Pflamm-Altenburg   +2 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Spectroscopic and Photometric Confirmation of 3 Globular and 14 Intermediate-age Clusters in the Irr II Galaxy NGC 3077

The Astronomical Journal
We present the results from spectroscopic and photometric analysis of 17 globular cluster (GC) candidates in the Irr II galaxy NGC 3077. The GC candidates were selected on the Hubble Space Telescope images and were cleaned of foreground Galatic stars ...
P. A. Ovando, Y. D. Mayya, L. H. Rodríguez-Merino, L. Lomelí-Nuñez, B. Cuevas-Otahola, D. Rosa-González, L. Carrasco   +6 more
doaj   +1 more source

THE FORMATION AND DYNAMICAL EVOLUTION OF YOUNG STAR CLUSTERS [PDF]

, 2015
Recent observations have revealed a variety of young star clusters, including embedded systems, young massive clusters, and associations. We study the formation and dynamical evolution of these clusters using a combination of simulations and theoretical ...
Michiko S. Fujii, S. P. Zwart
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Star Clusters as Links between Galaxy Evolution and Star Formation Project. I. Numerical Method

The Astrophysical Journal
Stellar clusters are critical constituents within galaxies: They are the result of highest-density star formation, and through their spatially and temporally correlated feedback, they regulate their host galaxy evolution.
Marta Reina-Campos, Oleg Y. Gnedin, Alison Sills, Hui Li   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

PSR J1922+37: a 1.9 s Pulsar Discovered in the Direction of the Old Open Cluster NGC 6791

The Astrophysical Journal Letters
More than 300 pulsars have been discovered in Galactic globular clusters; however, none have been found in open clusters. Here we present results from a 20 hr survey of seven open clusters with the Five-hundred-meter Aperture Spherical radio Telescope ...
Xiao-Jin Liu, Rahul Sengar, Matthew Bailes, Ralph P. Eatough, Jianping Yuan, Na Wang, Weiwei Zhu, Lu Zhou, He Gao, Zong-Hong Zhu, Xing-Jiang Zhu   +10 more
doaj   +1 more source

Star Clusters in the Nearby Late-Type Galaxy NGC 1311

, 2007
Ultraviolet, optical and near infrared images of the nearby (D ~ 5.5 Mpc) SBm galaxy NGC 1311, obtained with the Hubble Space Telescope, reveal a small population of 13 candidate star clusters.
Ashman K. M. & Zepf S. E., Baade W., Binney J. & Merrifield M., Corbin M. R., de Jong R. S., de Vaucouleurs G., Koo D. C. & Kron R. G., Noll K., Paul B. Eskridge, Peter Anders, Richard de Grijs, Rogier A. Windhorst, Rolf A. Jansen, Stover R. J., Violet A. Mager   +14 more
core   +1 more source

Mass and Rate of Hierarchical Black Hole Mergers in Young, Globular and Nuclear Star Clusters

, 2021
Michela Mapelli, Filippo Santoliquido, Yann Bouffanais, Manuel Arca Sedda, María Celeste Artale, Alessandro Ballone   +5 more
openalex   +1 more source