Results 111 to 120 of about 1,296,799 (301)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

PSR J1922+37: a 1.9 s Pulsar Discovered in the Direction of the Old Open Cluster NGC 6791

open access: yesThe Astrophysical Journal Letters
More than 300 pulsars have been discovered in Galactic globular clusters; however, none have been found in open clusters. Here we present results from a 20 hr survey of seven open clusters with the Five-hundred-meter Aperture Spherical radio Telescope ...
Xiao-Jin Liu   +10 more
doaj   +1 more source

Mapping the dynamics, star-formation rates, and chemical properties of galaxies with integral field spectroscopy [PDF]

open access: yes, 2005
Major advances in the development of instruments for eight and ten meter class telescopes are revolutionising our understanding of galaxy formation. In particular, Integral Field Spectrographs (which produce a three dimensional {x, y, velocity) map of a ...
Swinbank, Anthony Mark   +1 more
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Revisiting Open Clusters within 200 pc in the Solar Neighborhood with Gaia DR3

open access: yesThe Astronomical Journal
In this study, we develop a membership identification method and apply it for 30 open clusters (OCs) within 200 pc of the Sun using astrometric data of Gaia DR3.
Penghui Liu   +5 more
doaj   +1 more source

Ecology of Open Star Clusters

open access: yes, 2012
poster"Ecology of star clusters" examines the interactions of stars, and what can be gleaned from those interactions about the evolution and ultimate fate of star clusters large and small.
Lehman, Fred   +2 more
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The Star Clusters as Links between Galaxy Evolution and Star Formation Project. I. Numerical Method

open access: yesThe Astrophysical Journal
Stellar clusters are critical constituents within galaxies: They are the result of highest-density star formation, and through their spatially and temporally correlated feedback, they regulate their host galaxy evolution.
Marta Reina-Campos   +3 more
doaj   +1 more source

Observer’s guide to star clusters

open access: yes, 2013
This book is for amateur astronomers of all expertise, from beginner to experienced. It is intended to be used at the telescope – small, medium, or large – or even by an observer using binoculars or the naked eye.
Inglis, Mike
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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