Results 91 to 100 of about 1,165,937 (254)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Binaries in Star Clusters: NGC 2158 [PDF]

open access: yes
openA large fraction of stars in both the solar neighborhood and star clusters are a part of binary systems, so developing a complete understanding of binaries is essential in order to properly describe stellar structure, stellar evolution, and the ...
MARCHUK, ANASTASIA VADIMOVNA
core  

Towards AMR Simulations of Galaxy Formation [PDF]

open access: yes, 2010
Numerical simulations present a fundamental building block of our modern theoretical understanding of the Universe. As such the work in this thesis is primarily concerned with understanding fundamental differences that lie between the different ...
MITCHELL, NIGEL,LEWIS   +1 more
core  

Stellar populations in star clusters

open access: yes, 2016
Stellar populations contain the most important information about star cluster formation and evolution. Until several decades ago, star clusters were believed to be ideal laboratories for studies of simple stellar populations (SSPs).
Deng, Li-Cai   +2 more
core   +1 more source

Sierra Club, Lone Star Chapter Newsletter

open access: yes, 2019
Newsletter from the Lone Star Chapter of Sierra Club regarding Big Thicket Committee with an article titled "Big Thicket Expansion Sought" from the Lone Star SierranThe Big Thicket Collection contains materials relating to the conservation of the Big ...
Sierra Club, Lone Star Chapter
core   +1 more source

Revisiting Open Clusters within 200 pc in the Solar Neighborhood with Gaia DR3

open access: yesThe Astronomical Journal
In this study, we develop a membership identification method and apply it for 30 open clusters (OCs) within 200 pc of the Sun using astrometric data of Gaia DR3.
Penghui Liu   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Investigation into Triggered Star Formation by Radiative Driven Implosion [PDF]

open access: yes, 2016
When massive stars form, they emit strong, hydrogen ionising radiation fields into their molecular cloud environment, forming HII regions. This is believed to be capable of inducing effects which can trigger further star formation through a process known
Kinnear, Timothy Michael
core  

VLA 22 GHz Imaging of Massive Star Formation in Local Wolf–Rayet Galaxies

open access: yesThe Astrophysical Journal
We present 22 GHz imaging of regions of massive star formation within the Local Wolf–Rayet Galaxy Sample, a NSF Karl G. Jansky Very Large Array survey of 30 local galaxies showing spectral features of Wolf–Rayet (WR) stars.
Nicholas G. Ferraro   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy