Results 71 to 80 of about 1,165,937 (254)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
On the heating efficiency derived from observations of young super star clusters in M82 [PDF]
, 2009 Here, we discuss the mechanical feedback that massive stellar clusters provide to the interstellar medium of their host galaxy. We apply an analytic theory developed in a previous study for M82-A1 to a sample of 10 clusters located in the central zone of
GUILLERMO TENORIO TAGLE +2 more
core
Emergence of a Lithium Dip in ∼35 Myr “Snake” Open Clusters
The Astrophysical Journal LettersWe report the discovery of a lithium dip (Li dip) in the stellar “Snake” (age = 35 ± 5 Myr), challenging the classical view that Li dips emerge only at ages ≳150 Myr.
Yun-Yi Zhang +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The Velocity Dispersion Profile of Nine Open Clusters in the Solar Neighborhood
The Astrophysical JournalWe analyze the velocity dispersion profiles of nine open clusters in the solar neighborhood using kinematic data from Gaia DR 3, aiming to identify potential dynamical signatures of stellar-mass black holes through a comparison of theoretical and ...
Bingqian Ma +4 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Rotation and Hα Emission in a Young SMC Cluster: A Spectroscopic View of NGC 330
The Astrophysical JournalWe present an analysis of high-resolution optical spectra recorded for 30 stars of the split extended main-sequence turnoff of the young (∼40 Myr) Small Magellanic Cloud globular cluster NGC 330.
Paul I. Cristofari +6 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Astrophysical Journalω Centauri, the most massive globular cluster in the Milky Way, has long been suspected to be the stripped nucleus of a dwarf galaxy that fell into the Galaxy a long time ago.
M. S. Nitschai +17 more
doaj +1 more source