Results 101 to 110 of about 1,165,937 (254)
The Astronomical JournalWe present the results from spectroscopic and photometric analysis of 17 globular cluster (GC) candidates in the Irr II galaxy NGC 3077. The GC candidates were selected on the Hubble Space Telescope images and were cleaned of foreground Galatic stars ...
P. A. Ovando +6 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Simulating molecular cloud regulated star formation in Galaxies [PDF]
, 2007 This thesis is primarily concerned with understanding the process of galaxy formation via the simulation of the interstellar medium, star formation and supernova feedback.
Booth, Craig Martin
core
The Astrophysical JournalAge-benchmark brown dwarf and planetary-mass-object spectroscopy is key to characterizing substellar evolution. In this paper, we present the JHK medium-resolution ( R ∼ 3000) spectra of 25 7–76 M _Jup (spectral types L3.0–M6.0) brown dwarfs and ...
Elena Manjavacas +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Forest Fire Clustering: A Novel Tool for Identifying Star Members of Clusters
The Astronomical JournalIn the era of a data-driven landscape, the development of an efficient and interpretable method has become a pivotal tool for robustly identifying memberships of clusters.
Xingyin Wei +8 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Young star clusters: Progenitors of globular clusters!?
, 2005 Star cluster formation is a major mode of star formation in the extreme conditions of interacting galaxies and violent starbursts. Young clusters are observed to form in a variety of such galaxies, a substantial number resembling the progenitors of ...
Anders, Peter +2 more
core +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source