Circulating Interleukin‐6 Levels and Timing of Acute Ischemic Stroke Onset
ABSTRACT Intravenous thrombolysis is the most widely available effective ischemic stroke treatment, but is approved only if given within 4.5 h from stroke onset. Many patients are not treated because stroke onset time is unknown. We evaluated the cytokine interleukin 6 (IL‐6) in circulating blood after acute ischemic stroke (AIS).
Robert G. Kowalski+15 more
wiley +1 more source
Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal. [PDF]
Vial T+8 more
europepmc +1 more source
The Road Not Taken: Misclassifying an Anti‐Seizure Medication as a Failure
ABSTRACT Objective To quantify how often anti‐seizure medications (ASMs) appear ineffective yet provide benefit when considering seizure frequency (SF) variability. Methods We used the CHOCOLATES seizure diary simulator to generate 100,000 patient seizure diaries that reflect natural SF variation in a heterogeneous population.
Christopher N. Henry+1 more
wiley +1 more source
CoO<sub>x</sub> clusters-decorated IrO<sub>2</sub> electrocatalyst activates NO<sub>3</sub><sup>-</sup> mediator for benzylic C-H activation. [PDF]
Mi Z+7 more
europepmc +1 more source
The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh+22 more
wiley +1 more source
A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML. [PDF]
Li XP+6 more
europepmc +1 more source
Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis
ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif+17 more
wiley +1 more source
<i>Bacillales</i> isolate genomes from the macroalga <i>Sargassum ilicifolium</i> found in Singaporean coastal seawater. [PDF]
Pereyra JPA+4 more
europepmc +1 more source