Results 31 to 40 of about 71,766 (252)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
An In-depth Investigation of the Primordial Cluster Pair ASCC 19 and ASCC 21
The Astronomical JournalUtilizing Gaia data from the literature, we report a new young (∼8.9 Myr) cluster pair, ASCC 19 and ASCC 21, located near the Orion star-forming complex. The clusters are separated by a 3D distance of 27.00 ± 7.51 pc.
Qingshun Hu +6 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Utilizing Voronoi Tessellations to Determine Radial Density Profiles
The Astronomical JournalWe have developed a novel method of determining 2D radial density profiles for astronomical systems of discrete objects using Voronoi tessellations. This Voronoi-based method was tested against the standard annulus-based method on five simulated systems ...
Veronika Dornan, William E. Harris
doaj +1 more source
The Astrophysical Journal, 2023 We present a photometric analysis of globular cluster 47 Tuc (NGC 104) using near-IR imaging data from the GeMS/GSAOI Galactic Globular Cluster Survey (G4CS), which is in operation at Gemini-South telescope.
Mirko Simunovic +7 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
On the Roles of Stellar Rotation and Binarity in NGC 2423's Main-sequence Turnoff Region
The Astrophysical JournalResearch has shown that many young and intermediate-age clusters (younger than ∼2 Gyr) have extended main sequences and extended main-sequence turnoffs (eMSTOs), which cannot be adequately described by a single isochrone. The reason for the extended main
Yutian Bu +4 more
doaj +1 more source
The Astronomical Journal, 2023 Wide-field and deep DECam multiband photometry, combined with HST data for the core of the Galactic globular cluster NGC 2808, allowed us to study the distribution of various stellar subpopulations and stars in different evolutionary phases out to the ...
Christian I. Johnson +9 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The Astrophysical Journal LettersA meta-analysis of seismic ages determined for individual stars in the well-studied open and globular clusters NGC 6819, NGC 6791, M67, M4, M19, M80, and M9 reveals both high variance across measurements and a possible discrepancy with independent ...
Jamie Tayar, Meridith Joyce
doaj +1 more source