Results 41 to 50 of about 1,165,937 (254)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

UOCS-XIX. A Multiwavelength Study of Open Cluster Trumpler 5: Cluster Properties and Exotic Populations

open access: yesThe Astronomical Journal
Trumpler 5 is a populous, intermediate-age (∼3 Gyr), metal-poor ([Fe/H] ∼ −0.4) open cluster, located at a distance of approximately ∼3050 pc. This is a well-studied cluster for its broadened main-sequence (MS) and blue straggler star (BSS) population ...
Komal Chand, Anju Panthi, Kaushar Vaidya
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Star clusters in the Magellanic Clouds - I. Parametrization and classification of 1072 clusters in the LMC

open access: yes, 2016
We have introduced a semi-automated quantitative method to estimate the age and reddening of 1072 star clusters in the Large Magellanic Cloud (LMC) using the Optical Gravitational Lensing Experiment III survey data.
Subramaniam, A.   +8 more
core   +1 more source

A Systematic Analysis of Star Cluster Disruption by Tidal Shocks. II. Predicting Star Cluster Dissolution Rates from a Time-series Analysis of Their Tidal Histories

open access: yesThe Astrophysical Journal
Most of the dynamical mass loss from star clusters is thought to be caused by the time variability of the tidal field (“tidal shocks”). Systematic studies of tidal shocks have been hampered by the fact that each tidal history is unique, implying both a ...
Jeremy J. Webb   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Star Cluster Population of M51: II. Age distribution and relations among the derived parameters [PDF]

open access: yes, 2005
We use archival Hubble Space Telescope observations of broad-band images from the ultraviolet (F255W-filter) through the near infrared (NICMOS F160W-filter) to study the star cluster population of the interacting spiral galaxy M 51.
Bastian, NJ   +4 more
core  

Open Cluster Study Using Gaia. I. Membership and Cluster Properties

open access: yesThe Astrophysical Journal
Star clusters are interesting laboratories to study star formation, single and binary stellar evolution, and stellar dynamics. We have used the exquisite data from Gaia’s Data Release 3 (DR3) to study 21 relatively rich and nearby open clusters with ...
Anindya Ganguly   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An In-depth Investigation of the Primordial Cluster Pair ASCC 19 and ASCC 21

open access: yesThe Astronomical Journal
Utilizing Gaia data from the literature, we report a new young (∼8.9 Myr) cluster pair, ASCC 19 and ASCC 21, located near the Orion star-forming complex. The clusters are separated by a 3D distance of 27.00 ± 7.51 pc.
Qingshun Hu   +6 more
doaj   +1 more source

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