Results 91 to 100 of about 3,456,836 (310)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Lightweight real-time detection method for coal flow blockage based on Star-YOLOv8
Stable operation of the scraper conveyor in the fully mechanized mining face is a key factor in advancing the intelligent construction of coal mines. Existing vision-based detection methods mainly focus on equipment pose monitoring and recognition, while
Yue ZHANG +6 more
doaj +1 more source
The Detection of Stars with Neutron Cores.
The gravitational red-shift of the spectral lines is considered as the only possible means to detect stars containing neutron cores, assuming that there are sufficient energy sources available to make the star bright enough to be detected at all. A star in this highly evolved state would contain energy enough to be detectable only for a limited time ...
openaire +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
STAR-YOLO: A High-Accuracy and Ultra-Lightweight Method for Brain Tumor Detection
Brain tumors are among the deadliest malignant neoplasms worldwide, and early detection is critical for improving treatment outcomes and patient prognosis.
Liyan Sun +4 more
doaj +1 more source

