Results 141 to 150 of about 3,456,836 (310)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Predictions for the Detectability of Milky Way Satellite Galaxies and Outer-Halo Star Clusters with the Vera C. Rubin Observatory

The Open Journal of Astrophysics
We predict the sensitivity of the Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) to faint, resolved Milky Way satellite galaxies and outer-halo star clusters.
Kabelo Tsiane, Sidney Mau, Alex Drlica-Wagner, Jeffrey L. Carlin, Peter S. Ferguson, Keith Bechtol, Ethan O. Nadler, Annika H. G. Peter, Yao-Yuan Mao, Adam J. Thornton, LSST Dark Energy Science Collaboration   +10 more
doaj   +1 more source

Review: the landscape of gravitational wave astronomy

Acta Polytechnica
The direct detection of gravitational waves from a binary black hole merger has opened a new window in observational astronomy. The first three observing runs of the LIGO/Virgo groundbased interferometers have produced a broad range of scientific ...
Rosa Poggiani
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Generation of Large-Aperture Turbulence Based on Telescopic Imaging Principles

IEEE Photonics Journal
With increasing demand for extreme magnitude detection, star sensors are moving towards larger apertures. However, improved detection accuracy highlights the significant impact of atmospheric turbulence during calibration and operation.
Xin Yu, Jiasu Li, Guoqiang He, Suping Bai, Lingyun Wang, Xiaolong Ni, Lianghua Wen, Jing Liang, Jiahui Wang   +8 more
doaj   +1 more source

Influence and detectability of parasitic stars

, 1977
Technical note written as input to the early studies of the ESA space astrometry project Hipparcos.
openaire   +2 more sources

Western Star, 1953-01-07

, 1953
Western Star, 1953-01 ...

core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Western Star, 1953-10-07

, 1953
Western Star, 1953-10 ...

core