Results 201 to 210 of about 168,570 (264)

Protocol for using the multi-cellular analysis toolbox in ImageJ for single-cell calcium imaging analysis. [PDF]

STAR Protoc
Hageter J, Horstick E.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Chemiluminescent Deoxyribozyme Sensors for DNA-Editing Enzymes. [PDF]

ACS Chem Biol
Jakubec M, Svoboda M, Kurfürst J, Svehlova K, Veverka V, Curtis EA.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Hospital wastewater-based surveillance as an early-warning system for toxigenic <i>Vibrio cholerae</i>: first detection, isolation, characterization, and traceback investigation in Beijing, China. [PDF]

Emerg Microbes Infect
Gao Q, Huang Y, Lv B, Zhang W, Liu B, Gao Z, Qu M, Li S, Hao D, Sun H, Zhou H, Pang B, Tang S, Kan B, Yang P, Wang Q, Zhang D.   +16 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Whole genome sequencing in animal health: applications, challenges, and future directions. [PDF]

BMC Vet Res
Charlier J, Antonopoulos A, Broeckx BJG, Pomerantz A, Fowler VL, Olexiouk V, Theuns S, Arnouts S.   +7 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Sarcopenia and Physical Function in Obstructive Sleep Apnea: A Single-Centre Cross-Sectional Study (The SOSA Study). [PDF]

Clin Respir J
Abdulsalam AJ, Ambardar R, Abdulsalam M, Khadadah S, Alkandari S, Abdulsalam A, Shehab D, Kara M, Özçakar L.   +8 more
europepmc   +1 more source