Results 251 to 260 of about 3,456,836 (310)

Stepwise Protocol for Alternative Splicing Analysis in Single-Cell SMART-Seq2 RNA-Seq Data. [PDF]

Bio Protoc
Walker MN, Hu B, Cheng SY, Song X.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Wavelength-scale noise-resistant on-chip spectrometer. [PDF]

Nat Commun
Yu J, Lo H, Chen W, Zhu C, Wu Y, Wang F, Wang C, Yan C, Dang C, Wen B, Cao H, Chong Y, Wang QJ.   +12 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

YOLO-Starfish: fish object detection learning complex underwater features. [PDF]

Sci Rep
Gong R, Xu J, Zheng Z, Zhang D.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

DebrisWatch II: Digging Deeper for Geosynchronous Debris. [PDF]

J Astronaut Sci
Blake JA, Cooke BF, Paragini C, Feline W, Onken CA, Pollacco D, Privett G, Yanagisawa T, Airey R, Apergis I, Armellin R, Beesley L, Chote P, Cutolo AM, Eves S, Fujiwara T, Kuroda D, Lockley IS, MacManus A, McCormac J, Mitchell MA, Nimura T, Nishiyama K, Okumura SI, Schildknecht T, Shrive B, Urakawa S, Veras D, Whitlock P, Wolf C.   +29 more
europepmc   +1 more source

Pavement Crack Detection Based on Star-YOLO11

Computers, Materials & Continua
Jiang Mi, Zhijian Gan, Pengliu Tan, Xin Chang, Zhi Wang, Haisheng Xie   +5 more
openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Observations of Exocomets. [PDF]

Space Sci Rev
Korth J, Norazman A, Bendahan-West R, Kennedy G, Madurga Favieres C, Iglesias D, Shubina O, Xu S, Roth NX.   +8 more
europepmc   +1 more source