Results 91 to 100 of about 1,116,232 (311)

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

The effect of environment on star forming galaxies at redshift 1 - First insight from PACS

open access: yes, 2011
We use deep 70, 100 and 160 um observations taken with PACS, the Photodetector Array Camera and Spectrometer on board of Herschel, as part of the PACS Evolutionary Probe (PEP) guaranteed time, to study the relation between star formation rate and ...
A. Bongiovanni   +113 more
core   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Star formation within globular clusters:discrete multiple bursts and top-light mass functions [PDF]

open access: yes, 2019
The observed discrete multiple stellar populations and internal abundance spreads in r- and s-process elements within globular clusters (GCs) have been suggested to be explained self-consistently by discrete star formation events over a longer timescale (10^8 yr).
arxiv   +1 more source

Multi-Wavelength Observations and Modeling of Loop I

open access: yesGalaxies, 2018
The article aims to overview the origin and current dynamical state of a giant structure on the northern galactic sky—the radio Loop I extending from ≈ − 45 ∘ to ≈ + 45 ∘ in longitudes and up to ≈ 80 ...
Yuri Shchekinov
doaj   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

The Role of Magnetic Field in Molecular Cloud Formation and Evolution

open access: yesFrontiers in Astronomy and Space Sciences, 2019
We review the role that magnetic field may have on the formation and evolution of molecular clouds. After a brief presentation and main assumptions leading to ideal MHD equations, their most important correction, namely the ion-neutral drift is described.
Patrick Hennebelle   +2 more
doaj   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Cluster formation versus star formation around six regions in the Large Magellanic Cloud [PDF]

open access: yesarXiv, 2002
We studied the stellar population and star clusters around six regions in the Large Magellanic Cloud (LMC) in order to understand the correlation between star formation and cluster formation episodes. We used the stellar data base of OGLE II LMC survey and the star cluster catalogues.
arxiv  

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