Ureteral orifice edema and stenting challenges in diabetic patients: Lessons from a case report. [PDF]
Guo S, Hu Y, Liu Z, Huang D, Yang W.
europepmc +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Macular star formation in diabetic patients with non-arteritic anterior ischemic optic neuropathy (NA-AION). [PDF]
Galvez-Ruiz A.
europepmc +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Potential impact of the Sagittarius dwarf galaxy on the formation of young O-rich stars. [PDF]
Sun T+12 more
europepmc +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Feedback mechanisms stopping the star formation in a pair of massive galaxies in the early Universe
Pérez-González P+21 more
europepmc +1 more source
Formation of free-floating planetary mass objects via circumstellar disk encounters. [PDF]
Fu Z, Deng H, Lin DNC, Mayer L.
europepmc +1 more source
Explosive ejection of matter associated with star formation in the Orion nebula
D. A. Allen, Michael Burton
openalex +1 more source
Open-aired synthesis of star-shaped poly[2-(methacryloyloxy)ethyl trimethylammonium chloride]. [PDF]
Fronczyk T+3 more
europepmc +1 more source