Results 51 to 60 of about 194,114 (263)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A chemical perspective on planet formation in reduced systems
Astronomy & AstrophysicsContext. The relative abundances of refractory elements in planets are widely assumed to reflect those of their host stars. However, because elements are classified according to their behaviour in the solar nebula, this implicitly assumes that ...
Zaveri Urja +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Astronomical JournalDeuterium fractionation, as studied through mono-deuterated methanol, is frequently used as a diagnostic tool to trace the physical conditions and chemical evolution of interstellar sources. This study investigates methanol deuteration in the disk around
Shaoshan Zeng +5 more
doaj +1 more source
Astronomy & AstrophysicsContext. Modeling how cold giant planets form around M dwarfs remains a challenge, both because their protoplanetary disks can lack sufficient mass and because such planets are expected to migrate inward while interacting with the disk.
Sanchez M. +4 more
doaj +1 more source
Early-forming Massive Stars Suppress Star Formation and Hierarchical Cluster Assembly
The Astrophysical Journal, 2023 Feedback from massive stars plays an important role in the formation of star clusters. Whether a very massive star is born early or late in the cluster formation timeline has profound implications for the star cluster formation and assembly processes. We
Sean C. Lewis +10 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Origin of the Shell Structure in the Primary Outflow from IRAS 15398−3359
The Astrophysical JournalIRAS 15398−3359, a Class 0 protostar in the Lupus I star-forming region, is associated with three generations of outflows. The primary outflow, i.e., the most recent one, shows an internal structure named the “shell structure” in the near-infrared ...
Tomoyuki Hanawa +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
, 2006 HST is very well tailored for observations of extragalactic star clusters. One obvious reason is HST's high spatial resolution, but equally important is the wavelength range offered by the instruments on board HST, in particular the blue and near-UV coverage which is essential for age-dating young clusters.
openaire +2 more sources