Results 81 to 90 of about 1,116,232 (311)

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

FEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley, Daniel H. Shain, Eric A. Klein   +2 more
wiley   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

Mapping Global Star Formation in the Interacting Galaxy Pair Arp32 [PDF]

, 2008
A multi-wavelength set of photometric data including UV (GALEX), optical, near-IR, infrared (Spitzer) and radio (VLA 20cm) images and spectroscopic observations are used to map the dust-obscured and unobscured star formation in the galaxy pair Arp 32 ...
Appleton, P., Choi, P., Damjanov, I., Fadda, D., Lacy, M., Marleau, F., Storrie-Lombardi, L., Yan, L.   +7 more
core  

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Present-Day Star Formation: Protostellar Outflows and Clustered Star Formation

, 2012
Stars form predominantly in clusters inside dense clumps of turbulent, magnetized molecular clouds. The typical size and mass of the cluster-forming clumps are \sim 1 pc and \sim 10^2 - 10^3 M_\odot, respectively. Here, we discuss some recent progress on
Li, Zhi-Yun, Nakamura, Fumitaka
core   +1 more source

The Reliability of [C II] as a Star Formation Rate Indicator

Open Astronomy, 2011
We present a calibration of the star formation rate (SFR) as a function of the [C II] 157.74 μm luminosity for a sample of 24 star-forming galaxies in the nearby universe.
De Looze Ilse, Baes Maarten, Fritz Jacopo, Bendo George J., Cortese Luca   +4 more
doaj   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

In Situ Formation of Star Clusters at z > 7 via Galactic Disk Fragmentation: Shedding Light on Ultracompact Clusters and Overmassive Black Holes Seen by JWST

The Astrophysical Journal Letters
We investigate the nature of star formation in gas-rich galaxies at z > 7 forming in a markedly overdense region, in the vicinity of a massive virialized halo already exceeding 10 ^12 M _⊙ , through the use of the very-high-resolution cosmological ...
Lucio Mayer, Floor van Donkelaar, Matteo Messa, Pedro R. Capelo, Angela Adamo   +4 more
doaj   +1 more source

A Disk Wind Driving the Rotating Molecular Outflow in CB 26

The Astrophysical Journal, 2023
We present the ^12 CO ( J = 2–1) sensitive molecular line and 1.3 mm continuum observations from the Submillimeter Array (SMA) of the bipolar outflow associated with the young star located in the Bok globule known as CB 26.
J. A. López-Vázquez, Luis A. Zapata, Chin-Fei Lee   +2 more
doaj   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

FEBS Letters, EarlyView.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin, Danielle M. Colussi, Peter B. Stathopulos   +2 more
wiley   +1 more source