Results 21 to 30 of about 47,546 (266)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Cosmic-Ray Propagation in Young Embedded Clusters

The Astrophysical Journal
This paper constructs a quantitative description for the geometrical properties of young stellar clusters using a Delaunay mesh. This approach defines the paths that connect cluster members and can be used to characterize the distribution of path lengths
Marco Fatuzzo, Fred C. Adams
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Explaining the Chemical Inventory of Orion KL through Machine Learning

The Astrophysical Journal, 2023
The interplay of the chemistry and physics that exists within astrochemically relevant sources can only be fully appreciated if we can gain a holistic understanding of their chemical inventories. Previous work by Lee et al.
Haley N. Scolati, Anthony J. Remijan, Eric Herbst, Brett A. McGuire, Kin Long Kelvin Lee   +4 more
doaj   +1 more source

Ices in star forming regions [PDF]

Symposium - International Astronomical Union, 1997
IR spectra of sources associated with molecular cloud material show a variety of absorption features attributed to simple molecules, such as H2O, CO, CH3OH, CO2, CH4, and OCS in icy grain mantles. These identifications are reviewed. These molecules are formed through accretion and reaction of gas phase species on grain surfaces.
A.G.G.M. Tielens, D.C.B. Whittet
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Way of Water: ALMA Resolves H2O Emission Lines in a Strongly Lensed Dusty Star-forming Galaxy at z ∼ 3.1

The Astrophysical Journal, 2023
We report Atacama Large Millimeter/submillimeter Array (ALMA) high-resolution (≲0.3″) observations of water emission lines p -H _2 O(2 _02 − 1 _11 ), o -H _2 O(3 _21 − 3 _12 ), p -H _2 O(4 _22 − 4 _13 ), in the strongly lensed galaxy HATLASJ113526.2 ...
Francesca Perrotta, Marika Giulietti, Marcella Massardi, Giovanni Gandolfi, Tommaso Ronconi, Maria Vittoria Zanchettin, Quirino D’ Amato, Meriem Behiri, Martina Torsello, Francesco Gabrielli, Lumen Boco, Vincenzo Galluzzi, Andrea Lapi   +12 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Thermal Effects of Ambipolar Diffusion during the Gravitational Collapse of a Radiative Cooling Filament

The Astrophysical Journal
In this study, we consider the effects of ambipolar diffusion during the gravitational collapse of a radiative cooling filamentary molecular cloud. Two separate configurations of magnetic field, i.e., axial and toroidal, are considered in the presence of
Mahmoud Gholipour
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source