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Mechanisms of star fruit (Averrhoa carambola) toxicity: A mini-review

Toxicon, 2020
The star fruit (Averrhoa carambola) is consumed in high amounts in Asia and Central/South America. It contains oxalic acid and caramboxin. In some individuals, its ingestion may lead to nephrotoxicity and neurotoxicity. The nephrotoxic effect is due to oxalate deposition in renal tubules resulting in acute tubular necrosis and interstitial nephritis ...
Pamodh Yasawardene   +2 more
exaly   +3 more sources

Flavonoids isolated from the fresh sweet fruit of Averrhoa carambola , commonly known as star fruit

Phytochemistry, 2018
Thirteen flavonoids were isolated from the fresh sweet fruit of Averrhoa carambola L. (Oxalidaceae), commonly known as star fruit, and their structures were determined by spectroscopic and chemical methods. 8-Carboxymethyl-(+)-epicatechin methyl ester, pinobanksin 3-O-β-d-glucoside, and carambolasides M-Q were undescribed structures.
Xuchao Jia, Haihui Xie, Yueming Jiang
exaly   +4 more sources

Star Fruits (Averrhoa carambola)

2023
Thai Journal of Emergency Medicine., 5, 2, 59 ...
Pornchanok Sirisantisamrid   +3 more
openaire   +1 more source

[MRI findings in star-fruit intoxication].

Journal of neuroradiology = Journal de neuroradiologie, 2008
Star-fruit ingestion has been previously reported to cause severe neurotoxicity in uremic patients with symptoms ranging from hiccups, vomiting and consciousness disturbances to refractory status epilepticus, coma and death. MRI examinations of five uremic patients with severe neurological disturbances following star-fruit intoxication were reviewed ...
C, Cassinotto   +5 more
openaire   +2 more sources

Mechanisms of star fruit-induced acute renal failure

Food and Chemical Toxicology, 2008
We have previously discovered that star fruit can induce oliguric acute renal failure. To investigate the mechanisms of star fruit-associated acute oxalate nephropathy, the nephrotoxic effect of star fruit was examined in both cellular experiments and animal models.
Hua-Chang, Fang   +7 more
openaire   +2 more sources

Acute oxalate nephropathy induced by star fruit in rats

American Journal of Kidney Diseases, 2001
In this study, we intend to establish a connection between star fruit and acute oxalate nephropathy and also investigate predisposing factors for its development. Male Sprague-Dawley rats of 180 to 200 g were assigned to four groups; namely, control, experimental, fasting, and water-deprivation groups.
H C, Fang   +8 more
openaire   +2 more sources

Enzymatic carotenoid cleavage in star fruit (Averrhoa carambola)

Phytochemistry, 2003
This paper presents the first description of an enzyme fraction exhibiting carotenoid cleavage activity isolated from fruit skin of Averrhoa carambola. Partial purification of the enzyme could be achieved by acetone precipitation, ultrafiltration (300 kDa, 50 kDa), isoelectric focusing (pH 3-10) and sodium dodecyl sulfate polyacrylamide gel ...
Peter, Fleischmann   +2 more
openaire   +2 more sources

TRANSIENT INHIBITION OF CYP3A IN RATS BY STAR FRUIT JUICE

Drug Metabolism and Disposition, 2006
Star fruit juice is a potent in vitro inhibitor of CYP3A; however, few reports are available on the inhibition of CYP3A activities by star fruit juice in vivo. Therefore, in this study, we investigated the CYP3A-mediated star fruit-drug interaction in vivo. The effect of star fruit juice on carbamazepine pharmacokinetics was examined in rats.
Muneaki, Hidaka   +9 more
openaire   +2 more sources

Acute Oxalate Nephropathy After Ingestion of Star Fruit

American Journal of Kidney Diseases, 2001
Acute oxalate nephropathy associated with ingestion of star fruit (carambola) has not been reported before. We report the first two cases. These patients developed nausea, vomiting, abdominal pain, and backache within hours of ingesting large quantities of sour carambola juice; then acute renal failure followed.
C L, Chen   +4 more
openaire   +2 more sources

PHYTOCHEMICAL STUDIES OF STAR FRUIT AVERRHOA CARAMBOLA L.

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, 2021
The paper deals with a phytochemical investigation on the fruit of Averrhoa carambola L. belonging to the family Oxalidaceae. Commonly known as “star fruit”. Fruits and leaves are used widely in Ayurveda preparations to pacify impaired Kapha, pitta, skin diseases, pruritis, worm infestations, diarrhea, vomiting, hemorrhoids, intermittent fever, over ...
B. Sravanthi, N. Lakshmi Bhavani
openaire   +1 more source

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