Results 41 to 50 of about 344,090 (225)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Star γ Covers and Their Applications to Selection Principles

Tatra Mountains Mathematical Publications
Abstract By imposing the star operator on γ covers, we establish the notion of st-γ covers. The interrelationships among many recent variants of γ covers have been identified, and various counterexamples have been shown to distinguish them. An investigation has been conducted on the basic topological attributes of these covers.
Datta, Tanmayee, Bal, Prasenjit, Ghosh, Arnab   +2 more
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

ON A CERTAIN STAR-K VARIANT OF A SELECTION PRINCIPLE

Rocky Mountain Journal of Mathematics
arXiv admin note: substantial text overlap with arXiv:2207 ...
Chandra, Debraj, Alam, Nur
openaire   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Star-galaxy separation in the AKARI NEP Deep Field [PDF]

, 2012
Context: It is crucial to develop a method for classifying objects detected in deep surveys at infrared wavelengths. We specifically need a method to separate galaxies from stars using only the infrared information to study the properties of galaxies, e ...
A. Pollo, A. Pȩpiak, A. Solarz, Arendt, Barger, Bertin, Bertin, C. P. Pearson, Clements, Dole, Ellis, Frayer, Gao, H. Hanami, H. Matsuhara, Hsu, Huertas-Company, Imai, Iye, Jones, Lonsdale, Matsuhara, McVittie, Miyazaki, Mo, Oliver, Onaka, Papovich, Pearson, Pollo, Puget, Reid, Ryle, S. Oyabu, T. Goto, T. Ishigaki, T. T. Takeuchi, T. Takagi, T. Wada, Takeuchi, Tanabé, Taniguchi, Valiante, Wada, Walker, White, Williams, Woźniak, Y. Ohyama, Zhang   +49 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The Imprint of Cosmic Reionization on Galaxy Clustering

, 2007
We consider the effect of reionization on the clustering properties of galaxy samples at intermediate redshifts (z~0.3-5.5). Current models for the reionization of intergalactic hydrogen predict that overdense regions will be reionized early, thus ...
A. Loeb, J. S. B. Wyithe, Kriss
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source