Results 51 to 60 of about 4,489 (256)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Compact Monolithic Star Tracker System
OpticsA compact, low-cost star tracker system tailored for small satellite applications was designed and prototyped. The system was designed with a fast f/1.2 aperture, a 20 × 13° field of view, and a theoretical angular resolution of 10 arcs—sufficient for ...
Kamil Zuber +4 more
doaj +1 more source
Efficient Star Identification Using a Neural Network
Sensors, 2020 The required precision for attitude determination in spacecraft is increasing, providing a need for more accurate attitude determination sensors.
David Rijlaarsdam +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Real-Time Hardware-in-the-Loop Tests of Star Tracker Algorithms
International Journal of Aerospace Engineering, 2013 This paper deals with star tracker algorithms validation based on star field scene simulation and hardware-in-the-loop test configuration. A laboratory facility for indoor tests, based on the simulation of star field scenes, is presented.
Giancarlo Rufino +5 more
doaj +1 more source
Focal Adjustment for Star Tracker
Defence Science Journal, 2010 Technique of measuring intensity distribution and size of spot image developed has been discussed, which is especially suitable for defocus adjustment in ground test of star tracker. A novel approach for choosing a proper defocusing position has been proposed based on collimator, Gaussian surface fitting method, and other ordinary instruments.
Liu Hai-bo +6 more
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source