Kinetics of Heterogeneous Background in Stargardt’s Disease over Time [PDF]
Life, 2022 Stargardt’s disease (STGD1) is caused by mutations in the ABCA4 gene. Different lesions characterised by decreased autofluorescence levels are found in fundus autofluorescence (FAF) from STGD1 patients and could be used as outcome indicators for disease ...
Eduardo Rodríguez-Bocanegra +5 more
doaj +2 more sources
Reading strategies in Stargardt's disease with foveal sparing [PDF]
BMC Research Notes, 2010 Background Subjects with a ring scotoma can use two retinal loci, a foveal and a peripheral, for reading. Our aim was to investigate the relative use of both retinal loci as a function of the spared foveal area size and the spatial resolution at both ...
Whatham Andrew R +5 more
doaj +2 more sources
Subretinal Fibrosis in Stargardt’s Disease with Fundus Flavimaculatus and ABCA4 Gene Mutation [PDF]
Case Reports in Ophthalmology, 2012 Purpose: To report on 4 patients affected by Stargardt’s disease (STGD) with fundus flavimaculatus (FFM) and ABCA4 gene mutation associated with subretinal fibrosis. Methods: Four patients with a diagnosis of STGD were clinically examined.
Settimio Rossi +6 more
doaj +2 more sources
Comparison between the preferential hyperacuity perimeter and the Amsler grid to detect age-related macular degeneration and Stargardt's disease [PDF]
Journal of Optometry, 2011 Purpose: To evaluate the ability of the preferential hyperacuity perimeter (PHP) and the Amsler grid to detect central scotomas in Stargardt's disease and age macular degeneration.
Eva Chamorro +2 more
doaj +2 more sources
Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autoradiography: Implication for the local treatment of Stargardt’s disease and dry age‐related macular degeneration [PDF]
Pharmacology Research & Perspectives, 2020 Age‐related macular degeneration (AMD) is the leading cause of blindness in older people in the developed world while Stargardt's disease (SD) is a juvenile macular degeneration and an orphan disease.
Sylvie Julien‐Schraermeyer +6 more
doaj +2 more sources
Perimetry of the Central Visual Field Using a Head-Mounted Open-Source Perimeter in Patients with Inherited Retinal Diseases [PDF]
VisionHead-mounted (“virtual reality”) perimeters (HMPs), based on standard consumer electronic hardware, are a cheaper alternative to standard automated perimetry. They have not been validated in patients with inherited retinal disease (IRDs), yet.
Cord Huchzermeyer +2 more
doaj +2 more sources
Depression and quality of life in individuals with Stargardt’s disease [PDF]
Jornal Brasileiro de Psiquiatria, 2020 Objectives To assess depression and quality of life in individuals with Stargardt’s disease (SD), macular dystrophy whose central vision loss begins in the first decades of life.
Mirela L. S. Gomes +5 more
doaj +1 more source
Multimodal Imaging in a Case of Stargardt’s Disease
Delhi Journal of Ophthalmology, 2022 Stargardt Disease is the most common macular dystrophy, and multimodal image can be used for diagnosis and monitoring of the disease.
Shruti Bhattacharya +3 more
doaj +1 more source
Vitamin A, systemic T-cells, and the eye: Focus on degenerative retinal disease
Frontiers in Nutrition, 2022 The first discovered vitamin, vitamin A, exists in a range of forms, primarily retinoids and provitamin carotenoids. The bioactive forms of vitamin A, retinol and retinoic acid, have many critical functions in body systems including the eye and immune ...
Arun J. Thirunavukarasu +4 more
doaj +1 more source
Inherited Macular Dystrophies in a Tertiary Care Centre
Journal of Nepal Health Research Council, 2020 Background: Inherited macular dystrophies constitute a group of diseases characterized by bilateral central visual loss with symmetrical macular abnormalities usually presenting in the first two decades of life.
Priyanka Shrestha +7 more
doaj +1 more source